In situ hybridisation using a biotinylated 1.8kb human cDNA clone in both normal and structurally abnormal chromosomes supports regional localisation of the gene for human C1-inhibitor to chromosome 11q11-q13.11.
This is a preview of subscription content, log in to check access.
Buy single article
Instant access to the full article PDF.
Price includes VAT for USA
Subscribe to journal
Immediate online access to all issues from 2019. Subscription will auto renew annually.
This is the net price. Taxes to be calculated in checkout.
Bock SC, Skriver K, Nielsen E, Wiman B, Donaldson VH, Eddy RL, Marriman J, Radziefiwska E, Huber R, Shows TB (1986) Human C1-inhibitor: primary structure, cDNA cloning and chromosomal localisation. Biochemistry 25:4292–4301
Boyd E, Theriault A, Goddard JP, Kalaitsidaki M, Spathas DH, Connor JM (1989) Chromosomal assignment of a glutamic acid transfer RNA (tRNAGlu) gene to 1p36. Hum Genet 81:153–156
Davis AE, Whitehead AS, Harrison RA, Danphinais A, Bruns GAP, Cicardi M, Rosen FS (1986) Human inhibitor of the first component, C1, characterisation of cDNA clones and localisation of the gene to chromosome 11. Proc Natl Acad Sci USA 83:3161–3165
Fukushima Y, Byers MG, Bock S, Shows TB (1987) The human C1 inhibitor gene (C1NH) is located at 11q12–13.1 (abstract). (9th International Workshop on Human Gene Mapping) Cytogenet Cell Genet 46:617
Garson JA, Berghe JA van den, Kemshead JT (1987) High resolution in situ hybridisation technique using biotinylated NHYC oncogene probe reveals periodic structure of HSRs in human neuroblastoma. Cytogenet Cell Genet 45:10–15
Kerr MA, Yeung-Laiwah AC (1987) C1-inhibitor deficiency and angio oedema. In: Whaley K (ed) Complement in health and disease. MTP Press, Lancaster, pp 53–78
About this article
Cite this article
Theriault, A., Whaley, K., McPhaden, A.R. et al. Regional assignment of the human C1-inhibitor gene to 11q11–q13.1. Hum Genet 84, 477–479 (1990). https://doi.org/10.1007/BF00195824
- Internal Medicine
- Metabolic Disease
- cDNA Clone
- Regional Localisation
- Abnormal Chromosome