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Encyclopedia of Lipidomics pp 1–20Cite as

Analysis of Vitamin D Metabolites by Mass Spectrometry

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Synonyms

Mass spectrometric analysis of vitamin D metabolites; Vitamin D metabolite analysis by mass spectrometry

Introduction

This chapter provides an overview of the state-of-the-art of mass spectral analysis of vitamin D and its metabolites. Most activities in the vitamin D analytical field today center around clinical measurements, and emphasis in the following sections is therefore placed on vitamin D in human samples, mostly from serum or plasma. Virtually all modern mass spectrometry analyses of vitamin D are performed using hyphenated liquid chromatography-tandem mass spectrometry (LC-MS/MS) techniques. Measurements using gas chromatography (GC)-MS are now rarely performed, mainly because of problems with compound degradations during analysis. For those readers interested in GC-MS of vitamin D compounds, the present authors refer to an excellent review by Vouros and coworkers (Gathungu et al. 2013). Food analysis is also not addressed in this chapter, as requirements are quite...

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Authors and Affiliations

  1. Institute for Bioanalytical Chemistry, Saarland University, Campus B2.2, 66123, Saarbrücken, Saarland, Germany

    Dietrich A. Volmer

  2. Department of Medicine II, Saarland University Medical Center, Homburg, Germany

    Caroline S. Stokes

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  1. Dietrich A. Volmer
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  2. Caroline S. Stokes
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Correspondence to Dietrich A. Volmer .

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  1. Yong Loo Lin School of Medicine Centre for Life Sciences, Singapore, Singapore

    Markus R. Wenk

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Volmer, D.A., Stokes, C.S. (2016). Analysis of Vitamin D Metabolites by Mass Spectrometry. In: Wenk, M. (eds) Encyclopedia of Lipidomics. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7864-1_107-1

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  • DOI: https://doi.org/10.1007/978-94-007-7864-1_107-1

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  • Publisher Name: Springer, Dordrecht

  • Online ISBN: 978-94-007-7864-1

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