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Precise Biopatterning with Plasma: The Plasma Micro-contact Patterning (PμCP) Technique

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Encyclopedia of Nanotechnology

Synonyms

Bio-adhesion; Biopatterning; Cell adhesion; Cell micro-patterning; Cell patterning; Molecular patterning; Nano-patterning; Plasma micro-contact patterning; Plasma patterning; PmCP; PuCP; PμCP; Surface micro-patterning

Definition

Plasma micro-contact patterning (PμCP) is a simple, efficient, and cost-effective method for the precise patterning of molecules on surfaces. It combines the use of low-pressure plasma with an elastomeric 3D mask to spatially control the removal of molecules, such as proteins, from a surface. The entire PμCP process is subdivided into three main steps: surface pre-coating, plasma micro-patterning, and surface post-coating. Surfaces are first pre-coated with a molecular species and then placed in close contact with the 3D mask. This allows the formation of two distinct regions: an unmasked open region which is accessible to the plasma, from which the surface layer is removed, and a contact region which is physically protected from exposure to the...

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Correspondence to Remigio Picone .

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Picone, R., Baum, B., McKendry, R. (2015). Precise Biopatterning with Plasma: The Plasma Micro-contact Patterning (PμCP) Technique. In: Bhushan, B. (eds) Encyclopedia of Nanotechnology. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-6178-0_127-2

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  • DOI: https://doi.org/10.1007/978-94-007-6178-0_127-2

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  • Online ISBN: 978-94-007-6178-0

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