Skip to main content

Akute Pankreatitis: Klinik, Labordiagnostik und bildgebende Diagnostik

  • Living reference work entry
  • First Online:
Book cover DGIM Innere Medizin

Part of the book series: Springer Reference Medizin ((SRM))

  • 479 Accesses

Zusammenfassung

Die akute Pankreatitis stellt eine akute Entzündung des Pankreas dar, bei der es zu einer vollständigen Restitution des Organs kommt. Morphologisch kann eine ödematöse von einer nekrotisierenden Form der akuten Pankreatitis unterschieden werden. Im Rahmen der klinischen Diagnose, der ätiologischen Zuordnung und bei der Abschätzung des Schweregrads der Erkrankung kommen Labor- und bildgebenden Untersuchungen eine wichtige Rolle zu. In diesem Kapitel sollen die Bedeutung der klinischen Präsentation, der Labordiagnostik und der bildgebenden Diagnostik bei der Diagnose der akuten Pankreatitis dargestellt werden.

Dieser Beitrag basiert auf einem Kapitel, das die Autoren für das Werk Beger HG, Büchler MW, Dralle H, Lerch M, Malfertheiner P, Mössner J, Riemann JF (Hrsg.) (2014) Erkrankungen des Pankreas, Springer Heidelberg, geschrieben haben.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

Literatur

  • Al-Bahrani AZ, Ammori BJ (2005) Clinical laboratory assessment of acute pancreatitis. Clin Chim Acta Int J Clin Chem 362(1–2):26–48

    Article  CAS  Google Scholar 

  • Arvanitakis M, Delhaye M et al (2004) Computed tomography and magnetic resonance imaging in the assessment of acute pancreatitis. Gastroenterology 126(3):715–723

    Article  PubMed  Google Scholar 

  • Ayub K, Imada R et al (2004) Endoscopic retrograde cholangiopancreatography in gallstone-associated acute pancreatitis. Cochrane Database Syst Rev (4):CD003630

    Google Scholar 

  • Balthazar EJ, Robinson DL et al (1990) Acute pancreatitis: value of CT in establishing prognosis. Radiology 174(2):331–336

    Article  CAS  PubMed  Google Scholar 

  • Banks PA, Bollen TL et al (2013) Classification of acute pancreatitis – 2012: revision of the Atlanta classification and definitions by international consensus. Gut 62(1):102–111

    Article  PubMed  Google Scholar 

  • Block S, Maier W et al (1986) Identification of pancreas necrosis in severe acute pancreatitis: imaging procedures versus clinical staging. Gut 27(9):1035–1042

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Chang K, Lu W et al (2012) Rapid urinary trypsinogen-2 test in the early diagnosis of acute pancreatitis: a meta-analysis. Clin Biochem 45(13–14):1051–1056

    Article  CAS  PubMed  Google Scholar 

  • Clavien PA, Robert J et al (1989) Acute pancreatitis and normoamylasemia. Not an uncommon combination. Ann Surg 210(5):614–620

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Dervenis C, Johnson CD et al (1999) Diagnosis, objective assessment of severity, and management of acute pancreatitis. Santorini consensus conference. Int J Pancreatol 25(3):195–210

    CAS  PubMed  Google Scholar 

  • Elman R, Arneson N, Graham E (1929) Value of blood amylase estimations in the diagnosis of pancreatic disease: a clinical study. Arch Surg 19(6):943–967

    Article  CAS  Google Scholar 

  • Gomez D, Addison A et al (2012) Retrospective study of patients with acute pancreatitis: is serum amylase still required? BMJ Open 2(5)

    Google Scholar 

  • Gumaste VV, Dave PB et al (1991) Lipase/amylase ratio. A new index that distinguishes acute episodes of alcoholic from nonalcoholic acute pancreatitis. Gastroenterology 101(5):1361–1366

    CAS  PubMed  Google Scholar 

  • Jeffrey RB Jr (1989) Sonography in acute pancreatitis. Radiol Clin North Am 27(1):5–17

    PubMed  Google Scholar 

  • Koo BC, Chinogureyi A et al (2010) Imaging acute pancreatitis. Br J Radiol 83(986):104–112

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Kotwal V, Talukdar R et al (2010) Role of endoscopic ultrasound during hospitalization for acute pancreatitis. World J Gastroenterol 16(39):4888–4891

    Article  PubMed  PubMed Central  Google Scholar 

  • Lammert F, Neubrand MW et al (2007) S3-guidelines for diagnosis and treatment of gallstones. German Society for Digestive and Metabolic Diseases and German Society for Surgery of the Alimentary Tract. Z Gastroenterol 45(9):971–1001

    Article  CAS  PubMed  Google Scholar 

  • Lankisch PG (2009) Elevated pancreatic enzymes without evident pancreatic disease. Dtsch Med Wochenschr 134(44):2232–2235

    Article  CAS  PubMed  Google Scholar 

  • McMahon MJ, Pickford IR (1979) Biochemical prediction of gallstones early in an attack of acute pancreatitis. Lancet 2(8142):541–543

    Article  CAS  PubMed  Google Scholar 

  • Methuen T, Kylanpaa L et al (2007) Disialotransferrin, determined by capillary electrophoresis, is an accurate biomarker for alcoholic cause of acute pancreatitis. Pancreas 34(4):405–409

    Article  CAS  PubMed  Google Scholar 

  • Munoz-Bongrand N, Panis Y et al (2001) Serial computed tomography is rarely necessary in patients with acute pancreatitis: a prospective study in 102 patients. J Am Coll Surg 193(2):146–152

    Article  CAS  PubMed  Google Scholar 

  • Pandol SJ, Saluja AK et al (2007) Acute pancreatitis: bench to the bedside. Gastroenterology 132(3):1127–1151

    Article  CAS  PubMed  Google Scholar 

  • Sharma VK, Howden CW (1999) Metaanalysis of randomized controlled trials of endoscopic retrograde cholangiography and endoscopic sphincterotomy for the treatment of acute biliary pancreatitis. Am J Gastroenterol 94(11):3211–3214

    Article  CAS  PubMed  Google Scholar 

  • Spanier BW, Nio Y et al (2010) Practice and yield of early CT scan in acute pancreatitis: a Dutch Observational Multicenter Study. Pancreatology 10(2–3):222–228

    Article  CAS  PubMed  Google Scholar 

  • Spechler SJ, Dalton JW et al (1983) Prevalence of normal serum amylase levels in patients with acute alcoholic pancreatitis. Dig Dis Sci 28(10):865–869

    Article  CAS  PubMed  Google Scholar 

  • Steinberg WM, Goldstein SS et al (1985) Diagnostic assays in acute pancreatitis. A study of sensitivity and specificity. Ann Intern Med 102(5):576–580

    Article  CAS  PubMed  Google Scholar 

  • Stimac D, Lenac T et al (1998) A scoring system for early differentiation of the etiology of acute pancreatitis. Scand J Gastroenterol 33(2):209–211

    Article  CAS  PubMed  Google Scholar 

  • Sugumar A, Levy MJ et al (2011) Endoscopic retrograde pancreatography criteria to diagnose autoimmune pancreatitis: an international multicentre study. Gut 60(5):666–670

    Article  PubMed  Google Scholar 

  • Tenner S, Dubner H et al (1994) Predicting gallstone pancreatitis with laboratory parameters: a meta-analysis. Am J Gastroenterol 89(10):1863–1866

    CAS  PubMed  Google Scholar 

  • Van Gossum A, Seferian V et al (1984) Early detection of biliary pancreatitis. Dig Dis Sci 29(2):97–101

    Article  PubMed  Google Scholar 

  • Working Party of the British Society of Gastroenterology (2005) UK guidelines for the management of acute pancreatitis. Gut 54(Suppl 3):iii1–iii9

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Alexander Schneider .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer-Verlag Berlin Heidelberg

About this entry

Cite this entry

Schneider, A., Pfützer, R.H. (2015). Akute Pankreatitis: Klinik, Labordiagnostik und bildgebende Diagnostik. In: Lehnert, H., et al. DGIM Innere Medizin. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54676-1_95-1

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-54676-1_95-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-54676-1

  • eBook Packages: Springer Referenz Medizin

Publish with us

Policies and ethics