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Adrenal Steroid Hormones

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Drug Discovery and Evaluation: Pharmacological Assays

Abstract

The classical way to evaluate hormone function is to surgically ablate the hormone-producing endocrine gland and substitute it with exogenously administered substances (extracts or synthetic hormones) (Biedl 1916). Many studies on the physiological role of adrenocortical hormones and the pharmacological effects of corticosteroids were performed using adrenalectomized rats.

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  1. Centre of Pharmacology, Frankfurt-Main University, Glashuetten, Germany

    Jürgen Sandow

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  1. Jürgen Sandow
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  1. Dieburg, Germany

    Franz J. Hock

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Sandow, J. (2015). Adrenal Steroid Hormones. In: Hock, F. (eds) Drug Discovery and Evaluation: Pharmacological Assays. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27728-3_76-1

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