Keywords
- Unresponsive Wakefulness Syndrome (UWS)
- Minimally Conscious State
- Persistent Vegetative State
- Apallic Syndrome
- Brain Death
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Definition
Apallic syndrome is an older term that was first replaced by persistent vegetative state. More recently, unresponsive wakefulness syndrome (UWS) is the proposed nomenclature. The syndrome is a clinical condition describing patients who fail to show voluntary motor responsiveness in the presence of eyes-open wakefulness. Patients show reflexive behavior such as spontaneous breathing, but no signs of awareness of the self or the environment. A thorough clinical evaluation may be required to distinguish between UWS and other conditions, including coma, brain death, and locked-in syndrome.
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References and Readings
Multi-society task force on PVS (1994). Medical aspects of the persistent vegetative state-second of two parts. NEJM, 330, 1572–1579.
(1994). Medical aspects of the persistent vegetative state-first of two parts. NEJM, 330, 1499–1508.
Laureys, S., Celesia, G. G., Cohadon, F., Lavrijsen, J., et al. (2010). Unresponsive wakefulness syndrome: A new name for the vegetative state or apallic syndrome. BMC Medicine, 8, 68.
van Erp, W., Lavrijsen, J. C. M., van de Laar, F. A, Vos, P .E., Laureys S., Koopmans, R. T. C. M. (2014). The vegetative state/unresponsiveness wakefulness syndrome: A systematic review of prevalence studies. European Journal of Neurology, 21, 1361–1368.
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Locke, D. (2017). Appalic Syndrome. In: Kreutzer, J., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-56782-2_221-2
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DOI: https://doi.org/10.1007/978-3-319-56782-2_221-2
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