Definition
Gene-environment interactions (GxE) refer to instances in which the influence of a certain genotype depends on the environmental context, or vice versa: the influence of the environment depends on the individual’s genotype. Notably, the term “environment” refers to anything that is not genetic, e.g., nutrients, viruses, parenting, peers, culture, and the weather. Statistically, GxE are nonadditive influences of genetic and environmental factors on an individual’s characteristic, behavior, or disease.
Introduction
The understanding of GxE can help answer questions such as why a traumatic event leads certain individuals, but not others, to develop a posttraumatic stress disorder; why medications, treatments, and interventions only benefit some patients; why some teenagers appear to be more susceptible to peer pressure; and why children are not equally affected by abusive parenting. We briefly review the available designs for the study of GxE, present the possible forms GxE can...
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Avinun, R., Knafo-Noam, A. (2016). Gene-Environment Interaction. In: Zeigler-Hill, V., Shackelford, T. (eds) Encyclopedia of Personality and Individual Differences. Springer, Cham. https://doi.org/10.1007/978-3-319-28099-8_1471-1
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DOI: https://doi.org/10.1007/978-3-319-28099-8_1471-1
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