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Naming and Annotation of Plasmids

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Molecular Life Sciences

Synopsis

Genome sequences are being added to the public databases at phenomenal rates as sequencing becomes faster and cheaper. Plasmids are an important subset of extrachromosomal elements that often make significant contributions to the character of their hosts. Predicting these potential attributes depends on analyzing and cataloging the plethora of sequencing data in consistent and sensible ways. Currently, there is no consensus within the plasmid community on plasmid and gene names or how to handle the annotation of plasmids during the submission process to databases such as GenBank, but there are good models which can form the basis of a general naming system. It is also important to have clearer rules for the naming of plasmid core functions such as replication, partitioning, and conjugative transfer, among others. This entry explores these issues and makes some proposals for a more sustainable and rational system for plasmid naming, annotation, and analysis as consensus is...

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References

  1. Klimke W, O’Donovan C, White O et al (2011) Solving the problem: genome annotation standards before the data deluge. Stand Genomic Sci 5(1):168–193

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  2. Brister JR, Bao Y, Kuiken C et al (2010) Towards viral genome annotation standards, report from the 2010 NCBI annotation workshop. Viruses 2(10):2258–2268

    Article  PubMed Central  PubMed  Google Scholar 

  3. Sen D, Van der Auwera GA, Rogers LM et al (2011) Broad-host-range plasmids from agricultural soils have IncP-1 backbones with diverse accessory genes. Appl Environ Microbiol 77(22):7975–7983

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  4. Novick RP, Clowes RC, Cohen SN et al (1976) Uniform nomenclature for bacterial plasmids: a proposal. Bacteriol Rev 40(1):168–189

    CAS  PubMed Central  PubMed  Google Scholar 

  5. Achtman M, Willetts NS, Clark AJ (1971) Beginning a genetic analysis of conjugational transfer determined by the F factor in Escherichia coli by isolation and characterization of transfer-deficient mutants. J Bacteriol 106(2):529–538

    CAS  PubMed Central  PubMed  Google Scholar 

  6. Frost LS, Ippen-Ihler K, Skurray RA (1994) Analysis of the sequence and gene products of the transfer region of the F sex factor. Microbiol Rev 58(2):162–210

    CAS  PubMed Central  PubMed  Google Scholar 

  7. Pansegrau W, Lanka E, Barth PT et al (1994) Complete nucleotide sequence of Birmingham IncP alpha plasmids. Compilation and comparative analysis. J Mol Biol 239(5):623–663

    Article  CAS  PubMed  Google Scholar 

  8. Alvarez-Martinez CE, Christie PJ (2009) Biological diversity of prokaryotic type IV secretion systems. Microbiol Mol Biol Rev 73(4):775–808

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  9. Sciaky D, Montoya AL, Chilton MD (1978) Fingerprints of Agrobacterium Ti plasmids. Plasmid 1(2):238–253

    Article  CAS  PubMed  Google Scholar 

  10. Roberts RJ, Belfort M, Bestor T et al (2003) A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes. Nucleic Acids Res 31(7):1805–1812

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  11. Demerec M, Adelberg EA, Clark AJ et al (1966) A proposal for a uniform nomenclature in bacterial genetics. Genetics 54(1):61–76

    CAS  PubMed Central  PubMed  Google Scholar 

  12. Siguier P, Varani A, Perochon J et al (2012) Exploring bacterial insertion sequences with ISfinder: objectives, uses, and future developments. Methods Mol Biol 859:91–103

    Article  CAS  PubMed  Google Scholar 

  13. FTP directory of genomes/plasmids. ftp://ftp.ncbi.nih.gov/genomes/Plasmids/. Accessed 16 Mar 2014

  14. International Nucleotide Sequence Database Collaboration (INSDC). http://www.insdc.org/. Accessed 16 Mar 2014

  15. NCBI GenBank home page. http://www.ncbi.nlm.nih.gov/genbank/. Accessed 16 Mar 2014

  16. NCBI GenBank bacterial genome submission guide (annotation). http://www.ncbi.nlm.nih.gov/GenBank/genomesubmit_annotation. Accessed 16 Mar 2014

  17. NCBI GenBank bacterial genome submission guide (locus tag). http://www.ncbi.nlm.nih.gov/genbank/genomesubmit#locus_tag. Accessed 16 Mar 2014

  18. NCBI GenBank metagenome submission guide. http://www.ncbi.nlm.nih.gov/genbank/metagenome. Accessed 16 Mar 2014

  19. NCBI GenBank whole genome shotgun submissions guide. http://www.ncbi.nlm.nih.gov/genbank/wgs. Accessed 16 Mar 2014

  20. NCBI handbook. http://www.ncbi.nlm.nih.gov/books/NBK21105/. Accessed 16 Mar 2014

  21. NCBI reference sequence database. http://www.ncbi.nlm.nih.gov/RefSeq/. Accessed 16 Mar 2014

  22. Swiss-Prot Group http://web.expasy.org/groups/swissprot/. Accessed 16 Mar 2014

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Acknowledgments

The authors wish to thank Celeste Brown (University of Idaho), Bill Klimke (NCBI), and Miguel Cevallos (CFN, Mexico) for useful discussions.

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Correspondence to Laura S. Frost .

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© 2014 Springer Science+Business Media New York

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Frost, L.S., Thomas, C.M. (2014). Naming and Annotation of Plasmids. In: Bell, E. (eds) Molecular Life Sciences. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6436-5_568-2

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  • DOI: https://doi.org/10.1007/978-1-4614-6436-5_568-2

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  • Online ISBN: 978-1-4614-6436-5

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