Synopsis
NMR spectroscopy developed very rapidly during the past decades. Modern NMR spectroscopy is widely used in the structural biology. As one of the major methods for macromolecule structure determination at the atomic level, NMR is unique in its ability of determining the macromolecule structure in aqueous solution close to the physiological condition. The ability of detecting molecular motions of macromolecules on a large range of time scales makes NMR spectroscopy an ideal tool suitable not only for structure determination but also for molecular dynamics studies.
This short entry aims to briefly introduce the general process of solving a protein structure using NMR spectroscopy. Instead of emphasizing on the theory, the effort was put into an introduction of...
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Hu, Q. (2014). NMR Approaches to Determine Protein Structure. In: Bell, E. (eds) Molecular Life Sciences. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6436-5_32-2
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DOI: https://doi.org/10.1007/978-1-4614-6436-5_32-2
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Publisher Name: Springer, New York, NY
Online ISBN: 978-1-4614-6436-5
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