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Modes of DNA Base Pairing

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Molecular Life Sciences
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Synonyms

Canonical vs noncanonical DNA pairs; Non-Watson-Crick pairing

Definition

Included here are the interactions of bases and modified bases in the two (sometimes more) strands of DNA. These are usually driven by hydrogen bonding and stacking but can involve non-Watson-Crick pairing.

Discussion

The classic Watson-Crick G ≡ C and A = T pairings are taught in basic biochemistry and biology courses (Fig. 1). However, several other modes are possible.

Fig. 1
figure 1

Some modes of base pairing in DNA

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References

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Correspondence to F. Peter Guengerich .

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© 2014 Springer Science+Business Media New York

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Guengerich, F.P. (2014). Modes of DNA Base Pairing. In: Bell, E. (eds) Molecular Life Sciences. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6436-5_249-1

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  • DOI: https://doi.org/10.1007/978-1-4614-6436-5_249-1

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  • Online ISBN: 978-1-4614-6436-5

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