Insights into the Pharmacokinetics and Pharmacodynamics of Direct Oral Anticoagulants in Older Adults with Atrial Fibrillation: A Structured Narrative Review Angela Elma EdwinaNada DiaJos Tournoy Review Article 02 March 2023 Pages: 351 - 373
Alternative Methods for Therapeutic Drug Monitoring and Dose Adjustment of Tuberculosis Treatment in Clinical Settings: A Systematic Review Prakruti S. RaoNisha ModiJan-Willem C. Alffenaar Systematic Review Open access 04 March 2023 Pages: 375 - 398
The Pharmacokinetics and Target Attainment of Antimicrobial Drugs Throughout Pregnancy: Part III Non-penicillin and Non-cephalosporin Drugs F. GroenJ. R. PrinsP. Mian Systematic Review Open access 20 March 2023 Pages: 399 - 434
Integrated Pharmacokinetics/Pharmacodynamics Model and Simulation of the Ticagrelor Effect on Patients with Acute Coronary Syndrome Zhiyan LiuYaou LiuYimin Cui Original Research Article 03 February 2023 Pages: 435 - 447
The Effect of BMI on Pharmacokinetic and Pharmacodynamic Parameters of Insulin Degludec: Results from an Euglycemic Glucose Clamp Study Ting LiHui LiuYerong Yu Original Research Article 04 February 2023 Pages: 449 - 456
Can Mechanistic Static Models for Drug-Drug Interactions Support Regulatory Filing for Study Waivers and Label Recommendations? Jose David Gomez-MantillaFenglei HuangSheila Annie Peters Original Research Article Open access 08 February 2023 Pages: 457 - 480
Determination of the Optimal Single Dose Treatment for Acoziborole, a Novel Drug for the Treatment of Human African Trypanosomiasis: First-in-Human Study Antoine TarralLionel HovsepianNathalie Strub-Wourgaft Original Research Article Open access 10 February 2023 Pages: 481 - 491
Justifying Ribociclib Dose in Patients with Advanced Breast Cancer with Renal Impairment Based on PK, Safety, and Efficacy Data: An Innovative Approach Integrating Data from a Dedicated Renal Impairment Study and Oncology Clinical Trials Yan JiVitaly YartsevMichelle Miller Original Research Article Open access 17 February 2023 Pages: 493 - 504
A Model-Informed Approach to Accelerate the Clinical Development of Janagliflozin, an Innovative SGLT2 Inhibitor Ling SongXiaoxu WangDongyang Liu Original Research Article 18 February 2023 Pages: 505 - 518
Predictions of Bedaquiline and Pretomanid Target Attainment in Lung Lesions of Tuberculosis Patients using Translational Minimal Physiologically Based Pharmacokinetic Modeling Krina MehtaTingjie GuoJ. G. Coen van Hasselt Original Research Article Open access 19 February 2023 Pages: 519 - 532
