1. Etomidate and its Analogs: A Review of Pharmacokinetics and Pharmacodynamics

   • Beatrijs I. Valk
   • Michel M. R. F. Struys

   Review Article Open access 01 June 2021 Pages: 1253 - 1269

   

2. Antimicrobial Dose Reduction in Continuous Renal Replacement Therapy: Myth or Real Need? A Practical Approach for Guiding Dose Optimization of Novel Antibiotics

   • Milo Gatti
   • Federico Pea

   Review Article Open access 14 June 2021 Pages: 1271 - 1289

   

3. The Impact of Genetic Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Mycophenolic Acid: Systematic Review and Meta-analysis

   • Mingkwan Na Takuathung
   • Wannachai Sakuludomkan
   • Nut Koonrungsesomboon

   Systematic Review 09 June 2021 Pages: 1291 - 1302

   

4. The Effect of Modafinil on the Safety and Pharmacokinetics of Lorlatinib: A Phase I Study in Healthy Participants

   • Jerry Li
   • Yazdi K. Pithavala
   • Joseph Chen

   Original Research Article Open access 03 May 2021 Pages: 1303 - 1312

   

5. Pharmacokinetics of Lorlatinib After Single and Multiple Dosing in Patients with Anaplastic Lymphoma Kinase (ALK)-Positive Non-Small Cell Lung Cancer: Results from a Global Phase I/II Study

   • Joseph Chen
   • Melissa T. O’Gorman
   • Yazdi K. Pithavala

   Original Research Article Open access 03 May 2021 Pages: 1313 - 1324

   

6. Estimation of Clearance and Bioavailability of Therapeutic Monoclonal Antibodies from Only Subcutaneous Injection Data in Humans Based on Comprehensive Analysis of Clinical Data

   • Kenta Haraya
   • Tatsuhiko Tachibana

   Original Research Article Open access 06 May 2021 Pages: 1325 - 1334

   

7. Clinical Pharmacokinetics of Oral Semaglutide: Analyses of Data from Clinical Pharmacology Trials

   • Rune V. Overgaard
   • Andrea Navarria
   • Rasmus Juul Kildemoes

   Original Research Article Open access 10 May 2021 Pages: 1335 - 1348

   

8. Effect of Liver Cirrhosis on the Pharmacokinetics, Metabolism, and Tolerability of Daridorexant, A Novel Dual Orexin Receptor Antagonist

   • Benjamin Berger
   • Jasper Dingemanse
   • Stephan Krähenbühl

   Original Research Article 18 May 2021 Pages: 1349 - 1360

   

9. Current Ceftriaxone Dose Recommendations are Adequate for Most Critically Ill Children: Results of a Population Pharmacokinetic Modeling and Simulation Study

   • Stan J. F. Hartman
   • Parth J. Upadhyay
   • Saskia N. de Wildt

   Original Research Article Open access 26 May 2021 Pages: 1361 - 1372