1. Abuse and dependence potential of sphingosine-1-phosphate (S1P) receptor modulators used in the treatment of multiple sclerosis: a review of literature and public data

   • Kerri A. Schoedel
   • Carine Kolly
   • Kasra Shakeri-Nejad

   Review Open access 13 November 2021 Pages: 1 - 13

2. Psychedelics for the treatment of depression, anxiety, and existential distress in patients with a terminal illness: a systematic review

   • Nina Schimmers
   • Joost J. Breeksema
   • Robert A. Schoevers

   Review 23 November 2021 Pages: 15 - 33

   

3. An inpatient human laboratory study assessing the safety and tolerability, pharmacokinetics, and biobehavioral effect of GET 73 when co-administered with alcohol in individuals with alcohol use disorder

   • Carolina L. Haass-Koffler
   • Roberta Perciballi
   • Robert M. Swift

   Original Investigation 03 November 2021 Pages: 35 - 46

   

4. Therapeutic effect of Thymoquinone on behavioural response to UCMS and neuroinflammation in hippocampus and amygdala in BALB/c mice model

   • Sadia Nazir
   • Rai Khalid Farooq
   • Aneela Javed

   Original Investigation 14 January 2022 Pages: 47 - 58

   

5. Prospecting for a quinoline containing selenium for comorbidities depression and memory impairment induced by restriction stress in mice

   • Renata L. de Oliveira
   • Guilherme T. Voss
   • Cristiane Luchese

   Original Investigation 11 January 2022 Pages: 59 - 81

   

6. PCSK9 mediates dyslipidemia induced by olanzapine treatment in schizophrenia patients

   • Jing Huang
   • Jingmei Xiao
   • Renrong Wu

   Original Investigation 14 January 2022 Pages: 83 - 91

   

7. Effects of methamphetamine-induced neurotoxicity on striatal long-term potentiation

   • Anne S. Gibson
   • Peter J. West
   • Kristen A. Keefe

   Original Investigation Open access 05 January 2022 Pages: 93 - 104

   

8. “Push it!” or “Hold it!”? A comparison of nicotine-avoidance training and nicotine-inhibition training in smokers motivated to quit

   • Alla Machulska
   • Mike Rinck
   • Jürgen Margraf

   Original Investigation Open access 11 January 2022 Pages: 105 - 121

   

9. 5-HT_2C receptor perturbation has bidirectional influence over instrumental vigour and restraint

   • Oliver Härmson
   • Laura L. Grima
   • Mark E. Walton

   Original Investigation Open access 11 November 2021 Pages: 123 - 140

   

10. Effects of OPRM1 and DRD2 on brain structure in drug-naïve adolescents: Genetic and neural vulnerabilities to substance use

    • Giorgia Picci
    • Diana H. Fishbein
    • Emma J. Rose

    Original Investigation 24 November 2021 Pages: 141 - 152

    

11. Behavioral economic analysis of topiramate pharmacotherapy for alcohol: a placebo-controlled investigation of effects on alcohol reinforcing value and delayed reward discounting

    • Kimberly Goodyear
    • Robert Miranda Jr
    • James MacKillop

    Original Investigation 04 January 2022 Pages: 153 - 161

    

12. Neurochemical abnormalities in chronic fatigue syndrome: a pilot magnetic resonance spectroscopy study at 7 Tesla

    • Beata R. Godlewska
    • Stephen Williams
    • Philip J. Cowen

    Original Investigation Open access 05 October 2021 Pages: 163 - 171

    

13. Investigation of the risk of valproic acid–induced tremor: clinical, neuroimaging, and genetic factors

    • Lili Lan
    • Xu Zhao
    • Heidi E. Kirsch

    Original Investigation 30 October 2021 Pages: 173 - 184

    

14. Ketamine abrogates sensorimotor deficits and cytokine dysregulation in a chronic unpredictable mild stress model of depression

    • Edem Ekpenyong Edem
    • Collins-Kevin Chukwudi Anyanwu
    • Linus Anderson Enye

    Original Investigation 18 November 2021 Pages: 185 - 200

    

15. Reducing effect of the novel positive allosteric modulator of the GABA_B receptor, COR659, on binge-like alcohol drinking in male mice and rats

    • Irene Lorrai
    • Chase Shankula
    • Giancarlo Colombo

    Original Investigation 23 November 2021 Pages: 201 - 213

    

16. Sodium butyrate ameliorates the cognitive impairment of Alzheimer’s disease by regulating the metabolism of astrocytes

    • Chen Wang
    • Dongpeng Zheng
    • Ling He

    Original Investigation 23 November 2021 Pages: 215 - 227

    

17. Protease-activated receptor 2 activation induces behavioural changes associated with depression-like behaviour through microglial-independent modulation of inflammatory cytokines

    • Serge Moudio
    • Ashleigh Willis
    • Trevor J. Bushell

    Original Investigation Open access 09 December 2021 Pages: 229 - 242

    

18. Efficacy and safety of aripiprazole once-monthly versus oral aripiprazole in Chinese patients with acute schizophrenia: a multicenter, randomized, double-blind, non-inferiority study

    • Le Xiao
    • Qian Zhao
    • Gang Wang

    Original Investigation 06 January 2022 Pages: 243 - 251

    

19. Antidepressant activity of pharmacological and genetic deactivation of the small-conductance calcium-activated potassium channel subtype-3

    • Mina G. Nashed
    • Shannon Waye
    • José N. Nobrega

    Original Investigation 04 January 2022 Pages: 253 - 266

    

20. Targeting PSD95/nNOS by ZL006 alleviates social isolation-induced heightened attack behavior in mice

    • Luqi Yang
    • Jingyu Cui
    • Wen Lu

    Original Investigation 18 October 2021 Pages: 267 - 276

    

21. No antidepressant-like acute effects of bright light on emotional information processing in healthy volunteers

    • Alexander Kaltenboeck
    • Tereza Ruzickova
    • Catherine J. Harmer

    Original Investigation Open access 06 November 2021 Pages: 277 - 286

22. The zebrafish (Danio rerio) anxiety test battery: comparison of behavioral responses in the novel tank diving and light–dark tasks following exposure to anxiogenic and anxiolytic compounds

    • Barbara D. Fontana
    • Nancy Alnassar
    • Matthew O. Parker

    Original Investigation Open access 15 October 2021 Pages: 287 - 296

    

23. Involvement of oxidative pathways and BDNF in the antidepressant effect of carvedilol in a depression model induced by chronic unpredictable stress

    • Caren Nádia Soares de Sousa
    • Ingridy da Silva Medeiros
    • Silvânia Maria Mendes Vasconcelos

    Original Investigation 13 January 2022 Pages: 297 - 311

    

24. Mitragynine improves cognitive performance in morphine-withdrawn rats

    • Chiek Yi You
    • Zurina Hassan
    • Farah Wahida Suhaimi

    Original Investigation 25 October 2021 Pages: 313 - 325

    

25. Association between platelet MAO activity and lifetime drug use in a longitudinal birth cohort study

    • Katre Sakala
    • Kairi Kasearu
    • Jaanus Harro

    Original Investigation 10 January 2022 Pages: 327 - 337