Volume 16, Issue 4

Neurotherapeutics is now archived and no longer receiving submissions with this publisher. All articles published in the journal during its time with Springer will remain fully searchable through our websites.

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October 2019

Molecular Pathogenesis and Advances in Therapeutics of Tri-Nucleotide Repeat Expansion Disorders

32 articles in this issue

Letter from the Editor-in-Chief: Growth of the Journal
M. Maral Mouradian
EditorialNotes 13 September 2019 Pages: 923 - 923
Repeat Expansion Disorders: Mechanisms and Therapeutics
Lisa M. Ellerby
Editorial 06 January 2020 Pages: 924 - 927
Molecular Mechanisms and Therapeutics for SBMA/Kennedy’s Disease
Frederick J. Arnold
Diane E. Merry
Review Open access 04 November 2019 Pages: 928 - 947
DNA Damage Repair in Huntington’s Disease and Other Neurodegenerative Diseases
T. Maiuri
C. E. Suart
R. Truant
Review 30 July 2019 Pages: 948 - 956
Cell-Autonomous and Non-cell-Autonomous Pathogenic Mechanisms in Huntington’s Disease: Insights from In Vitro and In Vivo Models
Jordi Creus-Muncunill
Michelle E. Ehrlich
Review 16 September 2019 Pages: 957 - 978
Modeling Polyglutamine Expansion Diseases with Induced Pluripotent Stem Cells
Swati Naphade
Kizito-Tshitoko Tshilenge
Lisa M. Ellerby
Review 02 December 2019 Pages: 979 - 998
Moving Towards Therapy in SCA1: Insights from Molecular Mechanisms, Identification of Novel Targets, and Planning for Human Trials
Sharan R. Srinivasan
Vikram G. Shakkottai
Review 23 July 2019 Pages: 999 - 1008
From Pathogenesis to Novel Therapeutics for Spinocerebellar Ataxia Type 3: Evading Potholes on the Way to Translation
Jorge Diogo Da Silva
Andreia Teixeira-Castro
Patrícia Maciel
Review 05 November 2019 Pages: 1009 - 1031
Molecular Mechanisms and Therapeutics for the GAA·TTC Expansion Disease Friedreich Ataxia
Joel M. Gottesfeld
Review 17 July 2019 Pages: 1032 - 1049
Molecular Mechanisms and Therapeutics for Spinocerebellar Ataxia Type 2
Polina A. Egorova
Ilya B. Bezprozvanny
Review 21 August 2019 Pages: 1050 - 1073
Molecular Targets and Therapeutic Strategies in Spinocerebellar Ataxia Type 7
Anna Niewiadomska-Cimicka
Yvon Trottier
Review 20 August 2019 Pages: 1074 - 1096
Molecular Mechanisms and Therapeutics for SCA17
Qiong Liu
Yongcheng Pan
Shihua Li
Review 17 July 2019 Pages: 1097 - 1105
Molecular Mechanisms and Future Therapeutics for Spinocerebellar Ataxia Type 31 (SCA31)
Kinya Ishikawa
Yoshitaka Nagai
Review Open access 21 November 2019 Pages: 1106 - 1114
Pathogenic Mechanisms and Therapy Development for C9orf72 Amyotrophic Lateral Sclerosis/Frontotemporal Dementia
Jie Jiang
John Ravits
Review 30 October 2019 Pages: 1115 - 1132
The Medical Management of Cerebral Edema: Past, Present, and Future Therapies
Michael R. Halstead
Romergryko G. Geocadin
Current Perspectives 11 September 2019 Pages: 1133 - 1148
The Novel Small Molecule TRVA242 Stabilizes Neuromuscular Junction Defects in Multiple Animal Models of Amyotrophic Lateral Sclerosis
Poulomee Bose
Elsa Tremblay
Pierre Drapeau
Original Article 24 July 2019 Pages: 1149 - 1166
Biomarker Identification, Safety, and Efficacy of High-Dose Antioxidants for Adrenomyeloneuropathy: a Phase II Pilot Study
Carlos Casasnovas
Montserrat Ruiz
Aurora Pujol
Original Article Open access 10 May 2019 Pages: 1167 - 1182
Computer-Assisted Planning for Stereoelectroencephalography (SEEG)
Vejay N. Vakharia
Rachel Sparks
John S. Duncan
Original Article Open access 20 August 2019 Pages: 1183 - 1197
At-Home Cortical Stimulation for Neuropathic Pain: a Feasibility Study with Initial Clinical Results
Luis Garcia-Larrea
Caroline Perchet
Nathalie André-Obadia
Original Article 06 May 2019 Pages: 1198 - 1209
Transcranial Magneto-Acoustic Stimulation Improves Neuroplasticity in Hippocampus of Parkinson’s Disease Model Mice
Yuexiang Wang
Lina Feng
Zhuo Yang
Original Article 16 April 2019 Pages: 1210 - 1224
Tetramethylpyrazine Analogue T-006 Promotes the Clearance of Alpha-synuclein by Enhancing Proteasome Activity in Parkinson’s Disease Models
Hefeng Zhou
Min Shao
Simon Ming-Yuen Lee
Original Article 16 July 2019 Pages: 1225 - 1236
Long-Term Pantethine Treatment Counteracts Pathologic Gene Dysregulation and Decreases Alzheimer’s Disease Pathogenesis in a Transgenic Mouse Model
Kevin Baranger
Manuel van Gijsel-Bonnello
Philippe Benech
Original Article 02 July 2019 Pages: 1237 - 1254
Cyclooxygenase-2 Induced the β-Amyloid Protein Deposition and Neuronal Apoptosis Via Upregulating the Synthesis of Prostaglandin E₂ and 15-Deoxy-Δ^12,14-prostaglandin J₂
Pei-Pei Guan
Yun-Yue Liang
Pu Wang
Original Article 07 August 2019 Pages: 1255 - 1268
Activation of the miR-34a-Mediated SIRT1/mTOR Signaling Pathway by Urolithin A Attenuates d-Galactose-Induced Brain Aging in Mice
Peng Chen
Fuchao Chen
Benhong Zhou
Original Article 01 July 2019 Pages: 1269 - 1282
Glial Cell Line–Derived Neurotrophic Factor and Chondroitinase Promote Axonal Regeneration in a Chronic Denervation Animal Model
Karim A. Sarhane
Sami H. Tuffaha
Gerald Brandacher
Original Article 30 May 2019 Pages: 1283 - 1295
Perfusion Enhancement with Respiratory Impedance After Stroke (PERI-Stroke)
Christopher G. Favilla
Rodrigo M. Forti
Steven R. Messé
Original Article 28 May 2019 Pages: 1296 - 1303
Peripheral Administration of IL-13 Induces Anti-inflammatory Microglial/Macrophage Responses and Provides Neuroprotection in Ischemic Stroke
Natalia Kolosowska
Meike H. Keuters
Hiramani Dhungana
Original Article Open access 01 August 2019 Pages: 1304 - 1319
Induction of Neuronal PI3Kγ Contributes to Endoplasmic Reticulum Stress and Long-Term Functional Impairment in a Murine Model of Traumatic Brain Injury
Shan Liu
Rong Jin
Guohong Li
Original Article 11 June 2019 Pages: 1320 - 1334
Intranasal Neuropeptide Y Blunts Lipopolysaccharide-Evoked Sickness Behavior but Not the Immune Response in Mice
Geraldine Zenz
Aitak Farzi
Peter Holzer
Original Article Open access 23 July 2019 Pages: 1335 - 1349
Abstracts from HSG 2019

News 08 October 2019 Pages: 1350 - 1390
Correction to: Rescue of Methyl-CpG Binding Protein 2 Dysfunction-induced Defects in Newborn Neurons by Pentobarbital
Dongliang Ma
Su-In Yoon
Eyleen L. K. Goh
Correction 30 April 2019 Pages: 1391 - 1391
Correction to: Transcranial Magneto-Acoustic Stimulation Improves Neuroplasticity in Hippocampus of Parkinson’s Disease Model Mice
Yuexiang Wang
Lina Feng
Zhuo Yang
Correction 09 July 2019 Pages: 1392 - 1392

Volume 16, Issue 4

Letter from the Editor-in-Chief: Growth of the Journal

Repeat Expansion Disorders: Mechanisms and Therapeutics

Molecular Mechanisms and Therapeutics for SBMA/Kennedy’s Disease

DNA Damage Repair in Huntington’s Disease and Other Neurodegenerative Diseases

Cell-Autonomous and Non-cell-Autonomous Pathogenic Mechanisms in Huntington’s Disease: Insights from In Vitro and In Vivo Models

Modeling Polyglutamine Expansion Diseases with Induced Pluripotent Stem Cells

Moving Towards Therapy in SCA1: Insights from Molecular Mechanisms, Identification of Novel Targets, and Planning for Human Trials

From Pathogenesis to Novel Therapeutics for Spinocerebellar Ataxia Type 3: Evading Potholes on the Way to Translation

Molecular Mechanisms and Therapeutics for the GAA·TTC Expansion Disease Friedreich Ataxia

Molecular Mechanisms and Therapeutics for Spinocerebellar Ataxia Type 2

Molecular Targets and Therapeutic Strategies in Spinocerebellar Ataxia Type 7

Molecular Mechanisms and Therapeutics for SCA17

Molecular Mechanisms and Future Therapeutics for Spinocerebellar Ataxia Type 31 (SCA31)

Pathogenic Mechanisms and Therapy Development for C9orf72 Amyotrophic Lateral Sclerosis/Frontotemporal Dementia

The Medical Management of Cerebral Edema: Past, Present, and Future Therapies

The Novel Small Molecule TRVA242 Stabilizes Neuromuscular Junction Defects in Multiple Animal Models of Amyotrophic Lateral Sclerosis

Biomarker Identification, Safety, and Efficacy of High-Dose Antioxidants for Adrenomyeloneuropathy: a Phase II Pilot Study

Computer-Assisted Planning for Stereoelectroencephalography (SEEG)

At-Home Cortical Stimulation for Neuropathic Pain: a Feasibility Study with Initial Clinical Results

Transcranial Magneto-Acoustic Stimulation Improves Neuroplasticity in Hippocampus of Parkinson’s Disease Model Mice

Tetramethylpyrazine Analogue T-006 Promotes the Clearance of Alpha-synuclein by Enhancing Proteasome Activity in Parkinson’s Disease Models

Long-Term Pantethine Treatment Counteracts Pathologic Gene Dysregulation and Decreases Alzheimer’s Disease Pathogenesis in a Transgenic Mouse Model

Cyclooxygenase-2 Induced the β-Amyloid Protein Deposition and Neuronal Apoptosis Via Upregulating the Synthesis of Prostaglandin E₂ and 15-Deoxy-Δ^12,14-prostaglandin J₂

Activation of the miR-34a-Mediated SIRT1/mTOR Signaling Pathway by Urolithin A Attenuates d-Galactose-Induced Brain Aging in Mice

Glial Cell Line–Derived Neurotrophic Factor and Chondroitinase Promote Axonal Regeneration in a Chronic Denervation Animal Model

Perfusion Enhancement with Respiratory Impedance After Stroke (PERI-Stroke)

Peripheral Administration of IL-13 Induces Anti-inflammatory Microglial/Macrophage Responses and Provides Neuroprotection in Ischemic Stroke

Induction of Neuronal PI3Kγ Contributes to Endoplasmic Reticulum Stress and Long-Term Functional Impairment in a Murine Model of Traumatic Brain Injury

Intranasal Neuropeptide Y Blunts Lipopolysaccharide-Evoked Sickness Behavior but Not the Immune Response in Mice

Abstracts from HSG 2019

Correction to: Rescue of Methyl-CpG Binding Protein 2 Dysfunction-induced Defects in Newborn Neurons by Pentobarbital

Correction to: Transcranial Magneto-Acoustic Stimulation Improves Neuroplasticity in Hippocampus of Parkinson’s Disease Model Mice

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