1. An Alternative Explanation for Alzheimer’s Disease and Parkinson’s Disease Initiation from Specific Antibiotics, Gut Microbiota Dysbiosis and Neurotoxins

   • Kevin Roe

   Review 20 October 2021 Pages: 517 - 530

   

2. The Effect of α7nAChR Signaling on T Cells and Macrophages and Their Clinical Implication in the Treatment of Rheumatic Diseases

   • Shu Pan
   • Yi-Jin Wu
   • Jian Zuo

   Review 16 November 2021 Pages: 531 - 544

   

3. Spinal Microglia and Astrocytes: Two Key Players in Chronic Visceral Pain Pathogenesis

   • Jun-Yi Long
   • Xue-Jun Wang
   • Xiao-Peng Ma

   Review 19 November 2021 Pages: 545 - 551

   

4. Lipid-Based Nanocarriers via Nose-to-Brain Pathway for Central Nervous System Disorders

   • Thuy Trang Nguyen
   • Thi Thuy Dung Nguyen
   • Giau Van Vo

   Review 20 November 2021 Pages: 552 - 573

   

5. Comprehensive 16S rDNA Sequencing and LC–MS/MS-Based Metabolomics to Investigate Intestinal Flora and Metabolic Profiles of the Serum, Hypothalamus and Hippocampus in p‑Chlorophenylalanine-Induced Insomnia Rats Treated with Lilium brownie

   • Yanpo Si
   • Xiaohui Chen
   • Mengqi Liu

   Original Paper 18 October 2021 Pages: 574 - 589

   

6. Knock-Down of CD24 in Astrocytes Aggravates Oxyhemoglobin-Induced Hippocampal Neuron Impairment

   • Xiang-Xin Chen
   • Tao Tao
   • Wei Li

   Original Paper 19 October 2021 Pages: 590 - 600

   

7. ACE2 Rescues Impaired Autophagic Flux Through the PI3K/AKT Pathway After Subarachnoid Hemorrhage

   • Lujun Pang
   • Zhao Liu
   • Xin Qi

   Original Paper 27 October 2021 Pages: 601 - 612

   

8. Detailed Characterization of Brain Dysfunction in a Long-Term Rodent Model of Critical Illness

   • Renata C. Gonçalves
   • Celso Carneiro Carvalho Jr.
   • Felipe Dal-Pizzol

   Original Paper 21 October 2021 Pages: 613 - 621

   

9. Resiniferatoxin Hampers the Nocifensive Response of Caenorhabditis elegans to Noxious Heat, and Pathway Analysis Revealed that the Wnt Signaling Pathway is Involved

   • Jennifer Ben Salem
   • Bruno Nkambeu
   • Francis Beaudry

   Original Paper 25 October 2021 Pages: 622 - 633

   

10. Effect of P-glycoprotein Inhibition on the Penetration of Ceftriaxone Across the Blood–Brain Barrier

    • Yuheng Shan
    • Yuying Cen
    • Shengyuan Yu

    Original Paper 25 October 2021 Pages: 634 - 643

    

11. Neuroprotective Effect of Apigenin on Depressive-Like Behavior: Mechanistic Approach

    • Soroush Bijani
    • Rana Dizaji
    • Mir-Jamal Hosseini

    Original Paper 27 October 2021 Pages: 644 - 655

    

12. Long Non-coding RNA Peg13 Alleviates Hypoxic-Ischemic Brain Damage in Neonatal Mice via miR-20a-5p/XIAP Axis

    • Huan Gao
    • Yue Zhang
    • Xiaosan Bing

    Original Paper 19 January 2022 Pages: 656 - 666

    

13. The Influence of AA29504 on GABA_A Receptor Ligand Binding Properties and Its Implications on Subtype Selectivity

    • Sylvia Sikstus
    • Ali Y. Benkherouf
    • Mikko Uusi-Oukari

    Original Paper Open access 02 November 2021 Pages: 667 - 678

    

14. MiR-674-5p Suppresses the Proliferation and Migration of Glioma Cells by Targeting Cul4b

    • Wen Li
    • Juan Liu
    • Hui He

    Original Paper 15 November 2021 Pages: 679 - 691

    

15. Ferritinophagy is Involved in Experimental Subarachnoid Hemorrhage-Induced Neuronal Ferroptosis

    • Yidan Liang
    • Yongbing Deng
    • Zhaohui He

    Original Paper 06 November 2021 Pages: 692 - 700

    

16. Nimodipine Attenuates Early Brain Injury by Protecting the Glymphatic System After Subarachnoid Hemorrhage in Mice

    • Changkai Hou
    • Quanlei Liu
    • Xinyu Yang

    Original Paper 18 November 2021 Pages: 701 - 712

    

17. NLRP3 Inflammasome Activation Enhances ADK Expression to Accelerate Epilepsy in Mice

    • Haiju Zhang
    • Shiqian Yu
    • Baozhen Yao

    Original Paper 19 November 2021 Pages: 713 - 722

    

18. Ouabain-Na⁺/K⁺-ATPase Signaling Regulates Retinal Neuroinflammation and ROS Production Preventing Neuronal Death by an Autophagy-Dependent Mechanism Following Optic Nerve Axotomy In Vitro

    • Thalita Mázala-de-Oliveira
    • Camila Saggioro de Figueiredo
    • Elizabeth Giestal-de-Araujo

    Original Paper 16 November 2021 Pages: 723 - 738

    

19. Vitamin E Exerts Neuroprotective Effects in Pentylenetetrazole Kindling Epilepsy via Suppression of Ferroptosis

    • Xinfan Zhang
    • Shuhua Wu
    • Jianmin Li

    Original Paper 15 November 2021 Pages: 739 - 747

    

20. Hydroxysafflor Yellow A Inhibits Aβ_1–42-Induced Neuroinflammation by Modulating the Phenotypic Transformation of Microglia via TREM2/TLR4/NF-κB Pathway in BV-2 Cells

    • Mengqiao Ren
    • Mengyu Zhang
    • Yanli Hu

    Original Paper 16 November 2021 Pages: 748 - 761

    

21. Hyperhomocysteinemia Induces Rat Memory Impairment Via Injuring Hippocampal CA3 Neurons and Downregulating cAMP Response Element-Binding Protein (CREB) Phosphorylation

    • Chao Liu
    • Hong Zhao
    • Xin-Yu Yu

    Original Paper 17 November 2021 Pages: 762 - 767

    

22. Novel Somatostatin Receptor-4 Agonist SM-I-26 Mitigates Lipopolysaccharide-Induced Inflammatory Gene Expression in Microglia

    • Ashok Silwal
    • Austin House
    • Ken A. Witt

    Original Paper 30 November 2021 Pages: 768 - 780

    

23. Environmental Enrichment Differentially Activates Neural Circuits in FVB/N Mice, Inducing Social Interaction in Females but Agonistic Behavior in Males

    • Edith Araceli Cabrera-Muñoz
    • Sandra Olvera-Hernández
    • Gerardo Bernabé Ramírez Rodríguez

    Original Paper 03 January 2022 Pages: 781 - 794

    

24. Biochemical Alterations in White Matter Tracts of the Aging Mouse Brain Revealed by FTIR Spectroscopy Imaging

    • Kendra L. Furber
    • R. J. Scott Lacombe
    • Adil J. Nazarali

    Original Paper 24 November 2021 Pages: 795 - 810

    

25. Correction to: Reevaluation of Astrocyte‑Neuron Energy Metabolism with Astrocyte Volume Fraction Correction: Impact on Cellular Glucose Oxidation Rates, Glutamate–Glutamine Cycle Energetics, Glycogen Levels and Utilization Rates vs. Exercising Muscle, and Na⁺/K⁺ Pumping Rates

    • Gerald A. Dienel
    • Douglas L. Rothman

    Correction 19 January 2022 Pages: 811 - 812