1. A Double-Blind Study of the Sedative Effects of the Thalidomide Enantiomers in Humans

   • Peter Höglund
   • Tommy Eriksson
   • Sven Björkman

   OriginalPaper 01 August 1998 Pages: 363 - 383

2. Mathematical Formalism and Characteristics of Four Basic Models of Indirect Pharmacodynamic Responses for Drug Infusions

   • Wojciech Krzyzanski
   • William J. Jusko

   OriginalPaper 01 August 1998 Pages: 385 - 408

3. Characterization of Pharmacodynamic Recession Slopes for Direct and Indirect Response Models

   • Wojciech Krzyzanski
   • William J. Jusko

   OriginalPaper 01 August 1998 Pages: 409 - 436

4. A General Approach to Non-Markovian Compartmental Models

   • James H. Matis
   • Thomas E. Wehrly

   OriginalPaper 01 August 1998 Pages: 437 - 456

5. The Formulation of the Principle of Superposition in the Presence of Non-Compliance and Its Applications in Multiple Dose Pharmacokinetics

   • Wenping Wang
   • S. Peter Ouyang

   OriginalPaper 01 August 1998 Pages: 457 - 469

6. Use of a Pharmacokinetic/Pharmacodynamic Model to Design an Optimal Dose Input Profile

   • Kyungsoo Park
   • Davide Verotta
   • Lewis B. Sheiner

   OriginalPaper 01 August 1998 Pages: 471 - 492

7. Announcements

   Announcement 01 August 1998 Pages: 493 - 494