Abstract
We describe a mapping panel for the 8q23-qter region composed of human-hamster hybrid cell lines carrying deletion and translocation derivatives of human chromosome 8. The panel divides this region of the chromosome into nine intervals and has beenused to map 40 loci by Southern blot hybridization and PCR. Use of this mapping panel has allowed us to align the terminal portions of two different genetic maps of chromosome 8 with each other and with the physical map of the chromosome.
This is a preview of subscription content, log in via an institution to check access.
Literature Cited
Wagner, M.J., Ge, Y., Siciliano, M., and Wells, D.E. (1991).Genomics 10:114–125.
Parrish, J.E., Wagner, M.J., Hecht, J.T., Scott, C.I., Jr, and Wells, D.E. (1991).Genomics 11:54–61.
Lüdecke, H.-J., Johnson, C., Wagner, M.J., Wells, D.E., Turleau, C., Tommerup, N., Latos-Bielenska, A., Sandig, K.-R., Meinecke, P., Zabel, B., and Horsthemke, B. (1991).Am. J. Hum. Genet. 49:1197–1206.
Drabkin, H.A., Bradley, C., Hart, I., Bleskan, J., Li, F.P., and Patterson, D. (1985).Proc. Natl. Acad. Sci. U.S.A. 82:6980–6984.
Hudson, T.J., Engelstein, M., Lee, M.K., Ho, E.C., Rubenfield, M.J., Adams, C.P., Housman, D.E., and Dracopoli, N.C. (1992).Genomics 13:622–629.
Tomfohrde, J., Wood, S., Schertzer, M., Wagner, M.J., Wells, D.E., Parrish, J., Sadler, L.A., Blanton, S.H., Daiger, S.P., Wang, Z., Wilkie, P.J., and Weber, J.L. (1992).Genomics 14:144–152.
Weissenbach, J., Gyapay, G., Dib, C., Vignal, A., Morissette, J., Millasseau, P., Vaysseix, G., and Lathrop, M. (1992).Nature 359:794–801.
Hoppe, B.L., Conti-Tronconi, B.M., and Horton, R.M. (1992).BioTechniques 12:679–680.
Chua, S.C., Szabo, P., Vitek, A., Greschik, K.-H., John, M., and White, P.C. (1987).Proc. Natl. Acad. Sci. U.S.A. 84:7193–7197.
Alitalo, K., Schwab, M., Lin, C.C., Varmus, H.E., and Bishop, M.J. (1983).Proc. Natl. Acad. Sci. U.S.A. 80:1707–1711.
Baas, F., Bikker, H., Guerts van Kessel, A., Melsert, R., Pearson, P.L., de Vijlder, J.J.M., and van Ommen, G.-J.B. (1985).Hum. Genet. 69:138–143.
Lania, L., Donti, E., Pannuti, A., Pascucci, A., Pengue, G., Feliciello, I., La Mantia, G., Lanfrancone, L., and Pelicci, P.-G. (1990).Genomics 6:333–340.
NIH/CEPH Collaborative Mapping Group (1992).Science 258:67–86.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Parrish, J.E., Wang, Y., Wagner, M.J. et al. Alignment of physical and genetic maps of human 8q23-qter using somatic cell hybrid mapping panel. Somat Cell Mol Genet 20, 143–146 (1994). https://doi.org/10.1007/BF02290684
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02290684