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Demonstration of anti-hydralazine antibody in hydralazine inducedLupus erythematosus

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Résumé

La présence d'un facteur anti-hydralazine, probablement un anticorps, a été démontrée par l'emploi d'une technique d'hémagglutination dans le sérum d'un malade qui manifestait des symptômes de lupus érythémateux après un long traitement avec de l'hydralazine. Le même facteur anti-hydralazine a été observé dans le sérum des lapins qui avaient reçu des injections répétées d'émulsion d'hydralazine dans un adjuvant.

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Authors and Affiliations

  1. Departments of Microbiology and Cardiology, Albert Einstein Medical Center, Philadelphia, Pa., U.S.A.

    H. Friedman & W. I. Heine

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  1. H. Friedman
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  2. W. I. Heine
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Friedman, H., Heine, W.I. Demonstration of anti-hydralazine antibody in hydralazine inducedLupus erythematosus. Experientia 19, 10–11 (1963). https://doi.org/10.1007/BF02135326

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