Abstract
The primary sequences of the myoglobins of two rodents (the South American viscacha and the Mediterranean mole rat) have been determined. Both myoglobins exhibit one polymorphism. The two rodent sequences have been compared with each other and with other known myoglobins. The myoglobin of the viscacha is similar to those of the diving mammals and penguin in having a high arginine content. Among mammalian sequences, the arginines at positions 77 (in one of the viscacha myoglobins) and 79 have been found only in the myoglobin from viscacha. Mole rat myoglobin has a lysine at position 31, where arginine or serine is found in all other known vertebrate myoglobins.
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References
Chang, J. Y., Brauer, D., and Wittmann-Liebold, B. (1978).FEBS Lett. 93, 205–214.
Chang, J. Y., Knecht, R., and Braun, D. G. (1981).Biochem. J. 199, 547–555.
Clegg, J. B., Naughton, M. A., and Weatherall, D. J. (1966).J. Mol. Biol. 19, 91–108.
Dene, H., Goodman, M., and Romero-Herrera, A. E. (1980).Proc. R. Soc. Lond. B 207, 111–127.
Dene, H., Goodman, M., Walz, D. A., and Romero-Herrera, A. E. (1983).Hoppe-Seyler's Z. Physiol. Chem. 364, 1585–1595.
Dixon, H. B. F., and Perham, R. N. (1968).Biochem. J. 109, 312–314.
Goodman, M., Romero-Herrera, A. E., Dene, H., Czelusniak, J., and Tashian, R. E. (1982). InMacromolecular Sequences in Systematics and Evolutionary Biology (Goodman, M., ed.), Plenum Press, New York, pp. 115–191.
Gray, W. R. (1972).Meth. Enzymol. 25, 333–344.
Gurnett, A. M. (1983). Ph.D. Thesis, University of Cambridge.
Gurnett, A. M., O'Connell, J. P., and Lehmann, H. (1984). InBrussels Hemoglobin Symposium (Schnek, A. G., and Paul, C., eds.), Editions de l'Université de Bruxelles, Brussels, pp. 467–471.
Heinbokel, N., and Lehmann, H. (1984).FEBS Lett. 165, 46–50.
Joysey, K. A. (1984). InBrussels Hemoglobin Symposium (Schnek, A. G., and Paul, C., eds.), Éditions de l'Université de Bruxelles, Brussels, pp. 479–485.
Kleinschmidt, T., Nevo, E., and Braunitzer, G. (1984).Hoppe-Seyler's Z. Physiol. Chem. 365, 531–537.
Laemmli, U. K. (1970).Nature 227, 680–685.
Lehmann, H., and Huntsman, R. G. (1974).Man's Haemoglobins, North-Holland, Amsterdam, pp. 431–448.
Mahoney, W. C., and Hermodson, M. A. (1980).J. Biol. Chem. 255, 11199–11203.
Nevo, E. (1982). InMechanisms of Speciation (Barigozzi, C., ed.), Alan R. Liss, Inc., New York, pp. 191–218.
Romero-Herrera, A. E., Lehmann, H., Joysey, K. A., and Friday, A. E. (1978).Phil. Trans. R. Soc. B 283, 61–163.
Takano, T. (1977).J. Mol. Biol. 110, 537–568.
Wahrman, J., Goitein, R., and Nevo, E. (1969).Science 164, 82–83.
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Gurnett, A.M., O'Connell, J.P., Harris, D.E. et al. The myoglobin of rodents:Lagostomus maximus (viscacha) andSpalax ehrenbergi (mole rat). J Protein Chem 3, 445–454 (1984). https://doi.org/10.1007/BF01025063
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DOI: https://doi.org/10.1007/BF01025063