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Peripheral and central yestibular disorders in alcoholics

A three-year follow-up study

Periphere und zentrale Vestibularisstörungen bei Alkoholikern

Eine Kontrollstudie über drei Jahre

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Archives of oto-rhino-laryngology Aims and scope Submit manuscript

Zusammenfassung

Bei 33 männlichen Japanern, die länger als 20 Jahre Alkohol getrunken hatten und mehr als 3 Monate vor der Untersuchung abstinent waren, wurden vestibuläre Störungen gefunden. Periphere Störungen traten bei jungen Alkoholikern (unter 50 Jahren) bei einer Trinkzeit von 20–30 Jahren, kombinierte periphere und zentrale Störungen bei älteren Patienten mit langer Trinkanamnese auf. Bei 16 Nichtalkoholikern wurden keine vestibulären Störungen beobachtet. Eine Kontrollstudie bei sieben Alkoholikern mit dreijähriger Abstinenz zeigte eine Besserung besonders der peripheren vestibulären Störungen.

Summary

Vestibular disorders were found in all 33 Japanese men who had been drinking alcohol for over 20 years and who had abstained from alcohol for over 3 months before the tests were done. Six, 12, and 15 patients showed peripheral, central, and combined types of vestibular disorders, respectively. The peripheral disorder occurred in younger alcoholics (under 50 years old) with a drinking history of 20–30 years, and the combined disorder in older patients with a longer drinking history. The vestibular disorders, however, were not observed in any of 16 control non-alcoholics. A follow-up study on seven alcoholics with a 3-year abstinence from alcohol revealed an improvement of vestibular dysfunctions, in particular of peripheral disorders, with an abstinence of over 2 years.

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References

  • Bennett AE (1960) Diagnosis of intermediate stage of alcoholic brain disease. JAMA 172: 1143–1146

    Google Scholar 

  • Cala LA, Jones B, Maslaglia FL, Willey B (1978) Brain atrophy and intellectual impairment in heavy drinkers. A clinical, psychometric, and computerized tomography study. Aust NZ J Med 8: 147–153

    Google Scholar 

  • Carlen PL, Wortzman G, Holgate RC, Wilkinson DA, Rankin JG (1978) Reversible cerebral atrophy in recently abstinent chronic alcoholics measured by computed tomography scans. Science 200: 1076–1078

    Google Scholar 

  • Decker JB, Wells CE, McDowell F (1959) Cerebellar dysfunction associated with chronic alcoholism. Neurology 9: 361–366

    Google Scholar 

  • Dreyfus PM (1976) Thiamine-deficiency encephalopathy: thoughts on its pathogenesis. In: Gubler CJ, Fujiwara M, Dreyfus PM (eds) Thiamine. Wiley, New York, pp 229–241

    Google Scholar 

  • Fox JH, Ramsey RG, Huckman MS, Proske AE (1976) Cerebral ventricular enlargement. Chronic alcoholics examined by computerized tomography. JAMA 236: 365–368

    Google Scholar 

  • Freund G (1973) Chronic central nervous system toxicity of alcohol. Annu Rev Pharmacol 12: 217–227

    Google Scholar 

  • Ghez C (1969) Vestibular paresis: a clinical feature of Wernicke's disease. J Neurol Neurosurg Psychiatry 32: 134–139

    Google Scholar 

  • Haug JO (1968) Pneumoencephalographic evidence of brain damage in chronic alcoholism. Acta Psychiatr Scand [Suppl] 203: 135–143

    Google Scholar 

  • Ikeda Y, Sasa M, Takaori S (1980) Selective effect of ethanol on the vestibular nucleus neurons in the cat. Jp J Pharmacol 30: 665–673

    Google Scholar 

  • Nakai Y, Takeda Y, Takaori S (1973) Effects of ethanol on afferent transmission in the central visual pathway of cats. Eur J Pharmacol 21: 318–322

    Google Scholar 

  • Robinson DA (1973) Models of the saccadic eye movement control system. Kybernetik 14: 71–83

    Google Scholar 

  • Skillcorn SA (1958) Presenile cerebellar ataxia in chronic alcoholics. Neurology (Minneap) 5: 527–534

    Google Scholar 

  • Victor M, Adams RD, Mancall EL (1959) A restricted form of cerebellar cortical degeneration occurring in alcoholic patients. Arch Neurol 1: 579–688

    Google Scholar 

  • Victor M, Adams RD (1961) On the etiology of the alcoholic neurologic diseases, with special reference to the role of nutrition. Am J Clin Nutr 9: 379–397

    Google Scholar 

  • Victor M, Adams RD, Collins GH (1971) The Wernicke-Korsakoff syndrome: a clinical and pathological study of 245 patients, 82 postmortem examinations. Contemp Neurol Ser 7: 1–206

    Google Scholar 

Download references

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Sasa, M., Takaori, S., Matsuoka, I. et al. Peripheral and central yestibular disorders in alcoholics. Arch Otorhinolaryngol 230, 93–101 (1981). https://doi.org/10.1007/BF00665384

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  • DOI: https://doi.org/10.1007/BF00665384

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