Collection
Enhancing Health-span through Anti-Aging Dietary Interventions
- Submission status
- Open
- Open for submission from
- 20 June 2023
- Submission deadline
- Ongoing
We cordially invite the submission of original research articles, opinion papers, and review articles addressing the impact of diverse dietary interventions and eating patterns on age-related physiological decline in various organ systems, as well as their role in preventing and treating age-related diseases. Recent studies have demonstrated the remarkable potential of dietary interventions to induce biochemical and physiological changes that enhance organismal resilience and activate protective pathways. By slowing down cellular and molecular aging processes, these interventions can significantly contribute to the prevention of age-related diseases. More information are available HERE.
Editors
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Dr. Rafael de Cabo
National Institute on Aging, USA
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Dr. Stefano Tarantini
University of Oklahoma Health Science Center, USA
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Dr. Vincenzo Lionetti
Scuola Superiore Sant'Anna, Pisa, Italy
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Dr. Stefano Tarantini
University of Oklahoma Health Science Center, USA
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Dr. Vincenzo Lionetti
Scuola Superiore Sant'Anna, Pisa, Italy
Articles (50 in this collection)
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Reduction in metabolic noise reveals rejuvenation following transient severe caloric restriction
Authors (first, second and last of 8)
- Guy Levkovich
- Inna Bendikov-Bar
- Dror Sagi
- Content type: Original Article
- Open Access
- Published: 10 November 2023
- Pages: 2343 - 2358
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Antioxidants green tea extract and nordihydroguaiaretic acid confer species and strain-specific lifespan and health effects in Caenorhabditis nematodes
Authors (first, second and last of 29)
- Stephen A. Banse
- Christine A. Sedore
- Patrick C. Phillips
- Content type: Original Article
- Open Access
- Published: 04 November 2023
- Pages: 2239 - 2251
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The effect of glycine administration on the characteristics of physiological systems in human adults: A systematic review
Authors (first, second and last of 7)
- Janjira Soh
- Shivaanishaa Raventhiran
- Andrea B. Maier
- Content type: REVIEW
- Open Access
- Published: 18 October 2023
- Pages: 219 - 239
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Hawaiian native herb Mamaki prevents dementia by ameliorating neuropathology and repairing neurons in four different mouse models of neurodegenerative diseases
Authors (first, second and last of 5)
- Tomohiro Umeda
- Keiko Shigemori
- Takami Tomiyama
- Content type: ORIGINAL ARTICLE
- Published: 02 October 2023
- Pages: 1971 - 1987
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Salidroside promotes healthy longevity by interfering with HSP90 activity
Authors (first, second and last of 15)
- Jianfei Zhang
- Zhiquan Li
- Fangyin Dai
- Content type: ORIGINAL ARTICLE
- Published: 15 September 2023
- Pages: 1641 - 1655
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Mediterranean lifestyle index and 24-h systolic blood pressure and heart rate in community-dwelling older adults
Authors (first, second and last of 9)
- Irene Talavera-RodrÃguez
- José R. Banegas
- Mercedes Sotos-Prieto
- Content type: ORIGINAL ARTICLE
- Open Access
- Published: 10 August 2023
- Pages: 1357 - 1369
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Associations of sugar-sweetened, artificially sweetened, and naturally sweet juices with Alzheimer’s disease: a prospective cohort study
Authors (first, second and last of 7)
- Yanchun Chen
- Yuan Zhang
- Yaogang Wang
- Content type: ORIGINAL ARTICLE
- Published: 01 August 2023
- Pages: 1229 - 1240
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Calorie restriction mimetic drugs could favorably influence gut microbiota leading to lifespan extension
Authors (first, second and last of 4)
- Tomoya Shintani
- Hideya Shintani
- Hisashi Ashida
- Content type: REVIEW
- Open Access
- Published: 30 June 2023
- Pages: 3475 - 3490
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Serum factors mediate changes in mitochondrial bioenergetics associated with diet and exercise interventions
Authors (first, second and last of 6)
- Jenny L. Gonzalez-Armenta
- Jaclyn Bergstrom
- Anthony J. A. Molina
- Content type: ORIGINAL ARTICLE
- Open Access
- Published: 27 June 2023
- Pages: 349 - 365
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Curcumin-rich curry consumption and life expectancy: Singapore longitudinal ageing study
Authors (first, second and last of 6)
- Tze Pin Ng
- Shwe Zin Nyunt
- Keng Bee Yap
- Content type: ORIGINAL ARTICLE
- Published: 12 June 2023
- Pages: 969 - 980
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Sexual dimorphic metabolic and cognitive responses of C57BL/6 mice to Fisetin or Dasatinib and quercetin cocktail oral treatment
Authors (first, second and last of 9)
- Yimin Fang
- David Medina
- Erin R. Hascup
- Content type: ORIGINAL ARTICLE
- Open Access
- Published: 09 June 2023
- Pages: 2835 - 2850
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Long-term dasatinib plus quercetin effects on aging outcomes and inflammation in nonhuman primates: implications for senolytic clinical trial design
Authors (first, second and last of 11)
- Alistaire D. Ruggiero
- Ravichandra Vemuri
- Kylie Kavanagh
- Content type: ORIGINAL ARTICLE
- Published: 01 June 2023
- Pages: 2785 - 2803
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Alpha-ketoglutarate supplementation and BiologicaL agE in middle-aged adults (ABLE)—intervention study protocol
Authors (first, second and last of 8)
- Elena Sandalova
- Jorming Goh
- Andrea B. Maier
- Content type: ORIGINAL ARTICLE
- Open Access
- Published: 23 May 2023
- Pages: 2897 - 2907
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Cystine rather than cysteine is the preferred substrate for β-elimination by cystathionine γ-lyase: implications for dietary methionine restriction
Authors (first, second and last of 8)
- Thomas M. Jeitner
- Juan A. Azcona
- Arthur J. L. Cooper
- Content type: ORIGINAL ARTICLE
- Open Access
- Published: 23 May 2023
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Combining exercise with cognitive training and vitamin D3 to improve functional brain connectivity (FBC) in older adults with mild cognitive impairment (MCI). Results from the SYNERGIC trial
Authors (first, second and last of 11)
- Nick W. Bray
- Frederico Pieruccini-Faria
- Manuel Montero-Odasso
- Content type: ORIGINAL ARTICLE
- Published: 10 May 2023
- Pages: 1967 - 1985
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Unraveling effects of anti-aging drugs on C. elegans using liposomes
Authors (first, second and last of 7)
- Aihan Zhang
- Kuei Ching Hsiung
- David Gems
- Content type: ORIGINAL ARTICLE
- Open Access
- Published: 04 May 2023
- Pages: 1583 - 1603
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Moderate protein intake percentage in mice for maintaining metabolic health during approach to old age
Authors (first, second and last of 9)
- Yoshitaka Kondo
- Hitoshi Aoki
- Akihito Ishigami
- Content type: ORIGINAL ARTICLE
- Open Access
- Published: 28 April 2023
- Pages: 2707 - 2726
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Rapamycin restores peripheral blood flow in aged mice and in mouse models of atherosclerosis and Alzheimer’s disease
Authors (first, second and last of 4)
- Candice E. Van Skike
- Nicholas DeRosa
- Stacy A. Hussong
- Content type: Original Article
- Published: 13 April 2023
- Pages: 1987 - 1996
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Circulating polyunsaturated fatty acids, fish oil supplementation, and risk of incident dementia: a prospective cohort study of 440,750 participants
Authors (first, second and last of 10)
- Yu He
- Shu-Yi Huang
- Jin-Tai Yu
- Content type: ORIGINAL ARTICLE
- Published: 12 April 2023
- Pages: 1997 - 2009
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Geroprotective interventions in the 3xTg mouse model of Alzheimer’s disease
Authors
- Michelle M. Sonsalla
- Dudley W. Lamming
- Content type: Review
- Published: 06 April 2023
- Pages: 1343 - 1381
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Kinetic proteomics identifies targeted changes in liver metabolism and the ribo-interactome by dietary sulfur amino acid restriction
Authors (first, second and last of 9)
- William O. Jonsson
- Agnieszka K. Borowik
- Tracy G. Anthony
- Content type: Original Article
- Open Access
- Published: 28 March 2023
- Pages: 2425 - 2441
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Ketogenic diets initiated in late mid-life improved measures of spatial memory in male mice
Authors (first, second and last of 4)
- Zeyu Zhou
- Kyoungmi Kim
- Jennifer M. Rutkowsky
- Content type: ORIGINAL ARTICLE
- Open Access
- Published: 18 March 2023
- Pages: 2481 - 2494
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Four anti-aging drugs and calorie-restricted diet produce parallel effects in fat, brain, muscle, macrophages, and plasma of young mice
Authors (first, second and last of 6)
- Xinna Li
- Madaline McPherson
- Richard A. Miller
- Content type: ORIGINAL ARTICLE
- Published: 15 March 2023
- Pages: 2495 - 2510
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Preservation of mitochondrial membrane potential is necessary for lifespan extension from dietary restriction
Authors (first, second and last of 7)
- Brandon J. Berry
- Evan Mjelde
- Matt Kaeberlein
- Content type: ORIGINAL ARTICLE
- Published: 06 March 2023
- Pages: 1573 - 1581
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Intermittent treatment with elamipretide preserves exercise tolerance in aged female mice
Authors (first, second and last of 7)
- Matthew D. Campbell
- Ashton T. Samuelson
- David J. Marcinek
- Content type: Original Article
- Published: 25 February 2023
- Pages: 2245 - 2255
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Ultra-processed food consumption and nutritional frailty in older age
Authors (first, second and last of 14)
- Roberta Zupo
- Rossella Donghia
- Rodolfo Sardone
- Content type: ORIGINAL ARTICLE
- Open Access
- Published: 24 February 2023
- Pages: 2229 - 2243
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Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement verses whey protein in low physical functioning older adults
Authors (first, second and last of 10)
- Gohar Azhar
- Ambika Verma
- Jeanne Y. Wei
- Content type: ORIGINAL ARTICLE
- Open Access
- Published: 01 February 2023
- Pages: 1729 - 1743
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Testing the evidence that lifespan-extending compound interventions are conserved across laboratory animal model species
Authors
- Michael Bene
- Adam B. Salmon
- Content type: REVIEW
- Published: 13 January 2023
- Pages: 1401 - 1409
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The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial
Authors (first, second and last of 10)
- Lin Yi
- Andrea B. Maier
- Vidyadhar Kumbhar
- Content type: Original Article
- Open Access
- Published: 08 December 2022
- Pages: 29 - 43
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Morusin and mulberrin extend the lifespans of yeast and C. elegans via suppressing nutrient-sensing pathways
Authors (first, second and last of 15)
- Pingkang Xu
- Qimin Chen
- Ziyun Wu
- Content type: Original Article
- Published: 03 December 2022
- Pages: 949 - 964
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Rapamycin not dietary restriction improves resilience against pathogens: a meta-analysis
Authors
- Eleanor J. Phillips
- Mirre J. P. Simons
- Content type: Short Communication
- Open Access
- Published: 18 November 2022
- Pages: 1263 - 1270
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A long-term obesogenic high-fat diet in mice partially dampens the anti-frailty benefits of late-life intermittent fasting
Authors (first, second and last of 8)
- Yoko O. Henderson
- Nazmin Bithi
- Christopher Hine
- Content type: Short Communication
- Open Access
- Published: 26 October 2022
- Pages: 1247 - 1262
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Vitamin D3 promotes longevity in Caenorhabditis elegans
Authors
- Billy Huggins
- Mindy Farris
- Content type: Original Article
- Published: 24 August 2022
- Pages: 345 - 358
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Canagliflozin retards age-related lesions in heart, kidney, liver, and adrenal gland in genetically heterogenous male mice
Authors (first, second and last of 13)
- Jessica M. Snyder
- Kerriann M. Casey
- Warren Ladiges
- Content type: Original Article
- Open Access
- Published: 16 August 2022
- Pages: 385 - 397
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Which components of the Mediterranean diet are associated with dementia? A UK Biobank cohort study
Authors
- Ivelina Dobreva
- Louise Marston
- Naaheed Mukadam
- Content type: Original Article
- Open Access
- Published: 06 July 2022
- Pages: 2541 - 2554
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Plant-based diets and risk of frailty in community-dwelling older adults: the Seniors-ENRICA-1 cohort
Authors (first, second and last of 7)
- Javier Maroto-Rodriguez
- Mario Delgado-Velandia
- Mercedes Sotos-Prieto
- Content type: Original Article
- Open Access
- Published: 04 July 2022
- Pages: 221 - 232
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The PICLS high-throughput screening method for agents extending cellular longevity identifies 2,5-anhydro-D-mannitol as novel anti-aging compound
Authors
- Mohammad Alfatah
- Frank Eisenhaber
- Content type: Original Article
- Open Access
- Published: 15 June 2022
- Pages: 141 - 158
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Modulation of nigral dopamine signaling mitigates parkinsonian signs of aging: evidence from intervention with calorie restriction or inhibition of dopamine uptake
Authors (first, second and last of 12)
- Michael F. Salvatore
- Ella A. Kasanga
- Donald K. Ingram
- Content type: Original Article
- Published: 30 May 2022
- Pages: 45 - 63
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Vitamin D supplementation is associated with slower epigenetic aging
Authors (first, second and last of 6)
- Valentin Max Vetter
- Yasmine Sommerer
- Ilja Demuth
- Content type: Original Article
- Open Access
- Published: 13 May 2022
- Pages: 1847 - 1859
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Impact of medium-chain triglycerides on gait performance and brain metabolic network in healthy older adults: a double-blind, randomized controlled study
Authors (first, second and last of 8)
- Tatsushi Mutoh
- Keiko Kunitoki
- Yasuyuki Taki
- Content type: Original Article
- Published: 05 April 2022
- Pages: 1325 - 1338
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Integrative epigenomic and transcriptomic analyses reveal metabolic switching by intermittent fasting in brain
Authors (first, second and last of 27)
- Gavin Yong-Quan Ng
- Dominic Paul Lee Kok Sheng
- Thiruma V. Arumugam
- Content type: Original Article
- Published: 31 March 2022
- Pages: 2171 - 2194
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Evaluation of a blood-based geroscience biomarker index in a randomized trial of caloric restriction and exercise in older adults with heart failure with preserved ejection fraction
Authors (first, second and last of 9)
- Jamie N. Justice
- Nicholas M. Pajewski
- Dalane W. Kitzman
- Content type: Original Article
- Published: 10 January 2022
- Pages: 983 - 995
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Oolonghomobisflavans from Camellia sinensis increase Caenorhabditis elegans lifespan and healthspan
Authors
- Chatrawee Duangjan
- Sean P. Curran
- Content type: Original Article
- Open Access
- Published: 12 October 2021
- Pages: 533 - 545
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Pterocarpus marsupium extract extends replicative lifespan in budding yeast
Authors (first, second and last of 24)
- Mitchell B. Lee
- Michael G. Kiflezghi
- Matt Kaeberlein
- Content type: Original Article
- Published: 23 July 2021
- Pages: 2595 - 2609
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Eat like an athlete: insights of sports nutrition science to support active aging in healthy older adults
Authors (first, second and last of 4)
- Sara Y. Oikawa
- Tristin D. Brisbois
- Ian Rollo
- Content type: Review
- Open Access
- Published: 20 July 2021
- Pages: 2485 - 2495
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A small-molecule Psora-4 acts as a caloric restriction mimetic to promote longevity in C. elegans
Authors (first, second and last of 7)
- Tesfahun Dessale Admasu
- Diogo Barardo
- Jan Gruber
- Content type: Original Article
- Published: 14 May 2021
- Pages: 1029 - 1046
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Rapamycin restores brain vasculature, metabolism, and blood-brain barrier in an inflammaging model
Authors (first, second and last of 8)
- Rheal A. Towner
- Rafal Gulej
- Arlan Richardson
- Content type: Original Article
- Published: 13 April 2021
- Pages: 563 - 578
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Intermittent fasting: from calories to time restriction
Authors (first, second and last of 5)
- Eleonora Duregon
- Laura C.D. D. Pomatto-Watson
- Rafael de Cabo
- Content type: Review
- Published: 09 March 2021
- Pages: 1083 - 1092
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Late-life intermittent fasting decreases aging-related frailty and increases renal hydrogen sulfide production in a sexually dimorphic manner
Authors (first, second and last of 8)
- Yoko O. Henderson
- Nazmin Bithi
- Christopher Hine
- Content type: Original Article
- Open Access
- Published: 06 March 2021
- Pages: 1527 - 1554