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Meta-analysis on Therapy

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Talar Osteochondral Defects

Abstract

Treatment strategies for osteochondral lesions (OCL) of the ankle vary widely. Moreover, they have substantially increased over the past two decades, due to technical progress. In the case of a patient with a symptomatic OCL, it can be a challenge for the surgeon to choose from this wide pallet of treatment strategies. Publications are numerous, but often involve only one technique and therefore lack comparison. Stages of OCL vary between the studies, as do patient characteristics, surgical experience, and follow-up. Pooling the data of these studies can provide new information useful in decision making.

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Conflict of Interest

The author has no current conflict of interests with the products presented.

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Correspondence to Maartje Zengerink MD, PhD .

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Appendix 1: Newcastle-Ottawa Quality Assessment Scale

Appendix 1: Newcastle-Ottawa Quality Assessment Scale

Adjusted for Case Series

Study Design

  1. 1.

    Type of study

    1. (a)

      Prospective*

    2. (b)

      Retrospective

    3. (c)

      Other

    4. (d)

      Not described

  2. 2.

    Setup

    1. (a)

      According to protocol*

    2. (b)

      Without protocol

    3. (c)

      No protocol described

Selection

  1. 3.

    Representativeness of included patients

    1. (a)

      Truly representative of the average talar OCD patient in the community*

    2. (b)

      Somewhat representative of the average talar OCD patient in the community*

    3. (c)

      Selected group of patients by surgeon

    4. (d)

      No description of the derivation of the patient group

Outcome

  1. 4.

    Assessment of outcome

    1. (a)

      Independent blind assessment*

    2. (b)

      Record linkage*

    3. (c)

      Self-report

    4. (d)

      No description

  2. 5.

    Adequacy of follow-up of series

    1. (a)

      Complete follow-up – all subjects accounted for*

    2. (b)

      Subjects lost to follow-up unlikely to introduce bias – small number lost (<5 %)*

    3. (c)

      Follow-up rate <95 % and no description of those lost

    4. (d)

      No statement

Number of Assigned Stars

Study design (5)

Selection (6)

Outcome (7)

Every included study was separately assessed for quality using an adjusted version of the Newcastle-Ottawa Scale, as described above. It was performed by scoring each study for study design (0–2 stars), selection of patients (0–1 star), and outcome (0–2 stars). The designs that earned a star are marked with a *. For each study, the total number of stars is noted in the box above.

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Zengerink, M., van Dijk, C.N. (2014). Meta-analysis on Therapy. In: van Dijk, C., Kennedy, J. (eds) Talar Osteochondral Defects. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45097-6_10

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  • DOI: https://doi.org/10.1007/978-3-642-45097-6_10

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