Abstract
Therapeutic applications of nuclear medicine are expanding (Table 11.1). The radioisotopes in therapy were limited predominantly to treatment of hyperthyroidism and thyroid cancer, and polycythemia rubra vera for many years. Strontium 89 (Sr-89), rhenium 186 (Re-186), samarium 153 (Sm-153), and tin 117 m (Sn-117) have been increasingly used recently in treating bone pain secondary to metastases. Additionally, treatment of certain neuroendocrine tumors with I-131 MIBG and labeled octreotide and pentreotide, the use of radiolabeled monoclonal antibodies for lymphomas, and radionuclide synovectomy has revolutionized the field of therapeutic nuclear medicine.
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Further Reading
Brans B, Bacher K, Vandevyver V, Vanlangenhove P, Smeets P, Thierens H, Dierckx RA et al (2003) Intra-arterial radionuclide therapy for liver tumors: effect of selectivity of catheterization and 131I-Lipiodol delivery on tumor uptake and response. Nucl Med Commun 24:391–396
Elgazzar AH (2006) Therapeutic nuclear medicine. In: Elgazzar AH (ed) Pathophysiologic basis of nuclear medicine, 2nd edn. Springer, Berlin
Iagaru A, McDougall IR (2007) Treatment of thyrotoxicosis. J Nucl Med 48:379–389
Mothersill C et al (2006) Targeted radiotherapy: is the “holy grail” in sight? J Nucl Med 47:27N–27N
Shankar LK et al (2006) Consensus recommendations for the use of F-18 FDG PET as an indicator of therapeutic response in patients in national cancer institute trials. J Nucl Med 47:1059–1066
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Elgazzar, A.H. (2011). Therapeutic Applications of Nuclear Medicine. In: A Concise Guide to Nuclear Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-19426-9_11
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DOI: https://doi.org/10.1007/978-3-642-19426-9_11
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