Abstract
All methods for the generation of ions for mass spectrometry described up to this point require the analyte for ionization to be presented either directly under high vacuum (EI, CI, FI, FD) or contained in a sort of solution from which ions are to be extracted into or generated in the gas phase (FAB, LDI, MALDI). Even the atmospheric pressure ionization techniques employ processes that create ions from dilute (solid) solutions of the sample (ESI, APCI, APPI, AP-MALDI). This chapter deals with the manifold methods and interfaces which are allowing to overcome these limitations, and which have developed at a breathtaking pace within the short time since the publication of the first edition of this book.
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Gross, J.H. (2011). Ambient Mass Spectrometry. In: Mass Spectrometry. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-10711-5_13
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