Abstract
The diastole of the heart has captured the imagination of scientists ever since antiquity. Not surprisingly, the meaning of the word diastole has often been changed, as most scientific words change when novel experimental observations lead to new theories and concepts. At some instants in history, some physiologists even insisted that the terms systole and diastole ought to be banished altogether due to the confusion about the meaning and exact delineation of both phases in the overall cardiac cycle (1). Wiggers’s almost dogmatic subdivision of the cardiac cycle temporarily ended, however, an era of controversy, although he himself admitted that it was difficult to correlate end ejection with valve closure and to delineate where systole ceases and relaxation starts (Fig. 7.1).
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De Keulenaer, G.W., Brutsaert, D.L. (2008). Normal Physiology and Pathophysiology of Left Ventricular Diastole. In: Mebazaa, A., Gheorghiade, M., Zannad, F.M., Parrillo, J.E. (eds) Acute Heart Failure. Springer, London. https://doi.org/10.1007/978-1-84628-782-4_7
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DOI: https://doi.org/10.1007/978-1-84628-782-4_7
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