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Achieving Transcriptional Specificity in NF-κB-Dependent Inflammatory Gene Expression

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Vaccine Adjuvants

Part of the book series: Infectious Disease ((ID))

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Abstract

One of the most daunting problems in research on transcriptional regulation is to understand how specificity is achieved, that is, how a relatively small number of signal transduction pathways and transcription factors can activate transcription from different sets of genes in response to different stimuli.

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Author information

Authors and Affiliations

  1. Institute for Research in Biomedicine, Bellinzona, Switzerland

    Gioacchino Natoli MD

Authors
  1. Gioacchino Natoli MD
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Editor information

Editors and Affiliations

  1. Division of Allergy, Immunology, and Transplantation National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD

    Charles J. Hackett PhD

  2. Department of Immunology and Infectious Disease, Harvard School of Public Health, Boston, MA

    Donald A. Harn Jr. MD

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© 2006 Humana Press Inc., Totowa, NJ

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Natoli, G. (2006). Achieving Transcriptional Specificity in NF-κB-Dependent Inflammatory Gene Expression. In: Hackett, C.J., Harn, D.A. (eds) Vaccine Adjuvants. Infectious Disease. Humana Press. https://doi.org/10.1007/978-1-59259-970-7_3

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