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Regulation of Angiogenesis by Macrophages

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Retinal Degenerative Diseases

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 664))

Abstract

Abnormal angiogenesis is a cardinal feature in the pathophysiology of several diseases of the retina including retinopathy of prematurity, diabetic retinopathy and choroidal neovascularization associated with age-related macular degeneration. Recent evidence has implicated macrophages as components of the innate immune system that play a key role in regulating angiogenesis in the retina and choroid. This review will focus on the role of macrophages in regulating ocular angiogenesis.

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Correspondence to Rajendra S. Apte .

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Apte, R.S. (2010). Regulation of Angiogenesis by Macrophages. In: Anderson, R., Hollyfield, J., LaVail, M. (eds) Retinal Degenerative Diseases. Advances in Experimental Medicine and Biology, vol 664. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1399-9_2

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