Skip to main content

Mechanisms of Regulation of Taurine Transporter Activity

A Complex Interplay of Regulatory Systems

  • Conference paper
Taurine 6

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 583))

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 259.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

6. References

  • Alani, R., Brown, P., Binetruy, B., Dosaka, H., Rosenberg, R. K., Angel, P., Karin, M., and Birrer, M. J., 1991, The transactivating domain of the c-Jun proto-oncoprotein is required for cotransformation of rat embryo cells, Mol. Cell Biol. 11:6286–6295.

    PubMed  CAS  Google Scholar 

  • Bossy-Wetzel, E., Bakiri, L., and Yaniv, M., 1997, Induction of apoptosis by the transcription factor c-Jun, EMBO J. 16:1695–1709.

    Article  PubMed  CAS  Google Scholar 

  • Chesney, R. W., Gusowshi, N., and Friedman, A. L., 1983, Renal adaptation to altered sulfur amino acid intake occurs at luminal brushborder membrane, Kidney Int. 24:588–594.

    PubMed  CAS  Google Scholar 

  • Chesney, R. W., Gusowshi, N., and Dabbagh, S., 1985, Localization of the membrane defect in transepithelial transport of taurine by parallel studies in vivo and in vitro in hypertaurinuric mice, J. Clin. Invest. 76:2231–2221.

    Google Scholar 

  • Chesney, R. W., Lipincott, S., Gusowski, N., Padilla, M., and Zelikovic, I., 1986, Studies on renal adaptation to altered dietary amino acid intake: tissue taurine responses in nursing and adult rats, J. Nutr. 116:1965–1976.

    PubMed  CAS  Google Scholar 

  • Friedman, A. L., Jax, D. K., and Chesney, R. W., 1981, Developmental aspects of renal beta-amino acid transport. III. Ontogeny of transport in isolated renal tubule segments, Pediatr. Res. 15:10–13.

    PubMed  CAS  Google Scholar 

  • Friedman, A. L., Albright, P. W., Gusowski, N., Padilla, M., and Chesney, R. W., 1983, Renal adaptation to alteration in dietary amino acid intake, Am. J. Physiol. 245:F159–F166.

    PubMed  CAS  Google Scholar 

  • Godley, L. A., Eckhaus, M., Paglino, J. J., Owens, J., and Varmus, H. E., 1996, Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys, Genes Dev. 110:836–850.

    Google Scholar 

  • Han, X., Budreau, A. M., and Chesney, R. W., 1997, Adaptive regulation of MDCK cell taurine transporter (pNCT) mRNA: transcription of pNCT gene is regulated by external taurine concentration, Biochim. Biophys. Acta 1351:296–304.

    PubMed  CAS  Google Scholar 

  • Han, X., Budreau, A. M., and Chesney, R. W., 2000a, Identification of promoter elements involved in adaptive regulation of the taurine transporter gene: role of cytosolic Ca2+ signaling, Adv. Exp. Med. Biol. 483:535–44.

    Article  PubMed  CAS  Google Scholar 

  • Han, X., Budreau, A. M., and Chesney, R. W., 2000b, The taurine transporter gene and its role in renal development, Amino Acids 19:499–507.

    Article  PubMed  CAS  Google Scholar 

  • Hartl, M., Vogt, P. K., and Bister, K., 1995, A quail long-term cell culture transformed by a chimeric jun oncogene, Virology 207:321–326.

    Article  PubMed  CAS  Google Scholar 

  • Heller-Stilb, B., Van Roeyen, C., Rascher, K., Hartwig, H., Huth, A., Seeliger, M. W., Warskulat, D., and Haussinger, D., 2002, Disruption of the taurine transporter gene (taut) leads to retinal degeneration in mice, FASEB J. 16:231–233.

    PubMed  CAS  Google Scholar 

  • Jones, D. P., Miller, L. A., Dowling, C., and Chesney, R. W., 1991, Regulation of taurine transporter activity in LLC-PK1 cells: Role of protein synthesis and protein kinase C activation, J. Am. Soc. Nephrol. 2:2021–1029.

    Google Scholar 

  • Johnson, R., Spiegelman, B., Hanahan, D., and Wisdom, R., 1996, Cellular transformation and malignancy induced by ras require c-jun, Mol. Cell Biol. 16:4504–4511.

    PubMed  CAS  Google Scholar 

  • Kreidberg, J. A., Loring, S. H., Maeda, M., Pelletier, J., Housman, D., and Jaenisch, R., 1993, WT-1 is required for early kidney development, Cell 74:679–691.

    Article  PubMed  CAS  Google Scholar 

  • Learn, D. B., Fried, V. A., and Thomas, E. L., 1990, Taurine and hypotaurine content of human leukocytes, J. Leukoc. Biol. 48:174–182.

    PubMed  CAS  Google Scholar 

  • Maheswaran, S., Park, S., Bernard, N., Morris, J. F., Rauscher, F. J., Hill, D. E., and Haber, D. A., 1993, Physical and functional interaction between WT1 and p53 proteins, Proc. Natl. Acad. Sci. USA 90:5100–5104.

    Article  PubMed  CAS  Google Scholar 

  • Maheswaran, S., Englert, C., and Pelletier, R. J., 1995, The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis, Genes Dev. 9:2143–2156.

    PubMed  CAS  Google Scholar 

  • Rapp, U. R., Troppmair, J., Beck, T., and Birrer, M. J., 1994, Transformation by Raf and other oncogenes renders cells differentially sensitive to growth inhibition by a dominant negative c-jun mutant, Oncogene 9:3493–3498.

    PubMed  CAS  Google Scholar 

  • Smith, L. M., Wise, S. C. Hendricks, D. T. Sabichi, A. L. Bos, T. Reddy, P. Brown, P. H., and Birrer, M. J., 1999, cJun overexpression in MCF-7 breast cancer cells produces a tumorigenic, invasive and hormone resistant phenotype, Oncogene 18:6063–6070.

    Article  PubMed  CAS  Google Scholar 

  • Szabo, E., Preis, L. H. Brown, P. H. and Birrer, M. J., 1991, The role of jun and fos gene family members in 12-O-tetradecanoylphorbol-13-acetate induced hemopoietic differentiation, Cell Growth Differ. 2:475–482.

    PubMed  CAS  Google Scholar 

  • Wisdom, R., Johnson, R. S., and Moore, C., 1999, c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms, EMBO J. 18:188–197.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2006 Springer Science+Business Media, LLC

About this paper

Cite this paper

Han, X., Chesney, R.W. (2006). Mechanisms of Regulation of Taurine Transporter Activity. In: Oja, S.S., Saransaari, P. (eds) Taurine 6. Advances in Experimental Medicine and Biology, vol 583. Springer, Boston, MA . https://doi.org/10.1007/978-0-387-33504-9_8

Download citation

Publish with us

Policies and ethics