Conclusions
Arthroplasty of the whole knee improved motility and function in younger hemophilic patients [2].
Simultaneous bilateral arthroplasty was performed without intraoperative bleeding complications in patients with continuous infusion therapy of coagulation factor concentrates [3, 4].
We prefer continuous infusion compared to bolus injection in order to proof stable and sufficient plasma concentrations of coagulation factors [5].
Prospective studies are required to define state of arthropathy for the patients to undergo surgery, modus of surgery (unilateral or simultaneous bilateral arthroplasty), as well as material of endoprosthesis which has to be used.
Bilateral arthroplasty), as well as material of endoprosthesis which has to be used. Bilateral arthroplasty may be useful concerning postoperative functional training and cost reduction, but intraoperative hemorrhage could become a complication in case of insufficient substitution.
Data are requested whether continuous infusion or bolus injection provide more safety and comfort to patients and physicians.
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Wolf, H.H., Reichel, H., Dorligshaw, O., Schmoll, H.J. (2005). Orthopedic Knee Replacement in Hemophilic Patients. In: Scharrer, I., Schramm, W. (eds) 34th Hemophilia Symposium. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27022-1_12
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