Abstract
The surface of polyethylene slides nanocoated with silica and derivatized with long-chain poly(vinyl-N-hexylpyridinium) becomes permanently bactericidal: it kills 90–99% of (both airborne and waterborne) wild-type and antibiotic-resistant strains of the human pathogen Staphylococcus aureus. The material created was similarly lethal to strains expressing multidrug resistance pumps, the only known mechanism of resistance to cationic antiseptics.
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Lin, J., Tiller, J.C., Lee, S.B. et al. Insights into bactericidal action of surface-attached poly(vinyl-N-hexylpyridinium) chains. Biotechnology Letters 24, 801–805 (2002). https://doi.org/10.1023/A:1015584423358
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DOI: https://doi.org/10.1023/A:1015584423358