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Ibrutinib in Japanese patients with relapsed/refractory B-cell malignancies: final analysis of phase I study

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Reference

  1. Tobinai K, Ogura M, Ishizawa K, Suzuki T, Munakata W, Uchida T, et al. Safety and tolerability of ibrutinib monotherapy in Japanese patients with relapsed/refractory B cell malignancies. Int J Hematol. 2016;103:86–94.

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Acknowledgements

This study was funded by Janssen Pharmaceutical K.K. We thank the patients who participated in this trial and their families. Writing assistance was provided by Safeer Mughal, PhD, of PAREXEL, and was funded by Janssen Global Services. The data sharing policy of Janssen Pharmaceutical Companies of Johnson & Johnson is available at https://www.janssen.com/clinical-trials/transparency. As noted on this site, requests for access to the study data can be submitted through Yale Open Data Access (YODA) Project site at http://yoda.yale.edu.

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Correspondence to Kensei Tobinai.

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Conflict of interest

KT received grants and personal fees from Celgene, Chugai, Eisai, Janssen, Kyowa Hakko Kirin, Mundipharma, Ono, Takeda; personal fees from HUYA and Zenyaku Kogyo; grants from AbbVie, GSK SERVIER. NF received grants from Janssen. TU received personal fees from BMS, Celgene, Chugai, Eisai, Janssen, Kyowa Hakko Kirin, Novartis, Mundipharma, Nippon Shinyaku, Otsuka, Pfizer Takeda. TN is employed by Janssen.

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Trial registration

NCT01704963 (ClinicalTrials.gov).

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Tobinai, K., Uchida, T., Fukuhara, N. et al. Ibrutinib in Japanese patients with relapsed/refractory B-cell malignancies: final analysis of phase I study. Int J Hematol 109, 366–368 (2019). https://doi.org/10.1007/s12185-018-02577-8

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  • DOI: https://doi.org/10.1007/s12185-018-02577-8

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