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Seriously overestimated prognostic value of baseline and interim FDG-PET in diffuse large B cell lymphoma

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References

  1. Mikhaeel NG, Smith D, Dunn JT, Phillips M, Moller H, Fields PA, Wrench D, Barrington SF (2016) Combination of baseline metabolic tumour volume and early response on PET/CT improves progression-free survival prediction in DLBCL. Eur J Nucl Med Mol Imaging. doi:10.1007/s00259-016-3315-7

    PubMed  PubMed Central  Google Scholar 

  2. Sun N, Zhao J, Qiao W, Wang T (2015) Predictive value of interim PET/CT in DLBCL treated with R-CHOP: meta-analysis. Biomed Res Int 2015:648572. doi:10.1155/2015/648572

    PubMed  PubMed Central  Google Scholar 

  3. Mamot C, Klingbiel D, Hitz F, Renner C, Pabst T, Driessen C, Mey U, Pless M, Bargetzi M, Krasniqi F, Gigli F, Hany T, Samarin A, Biaggi C, Rusterholz C, Dirnhofer S, Zucca E, Martinelli G (2015) Final results of a prospective evaluation of the predictive value of interim positron emission tomography in patients with diffuse large B-cell lymphoma treated with R-CHOP-14 (SAKK 38/07). J Clin Oncol 33(23):2523–2529. doi:10.1200/JCO.2014.58.9846

    Article  CAS  PubMed  Google Scholar 

  4. Adams HJ, de Klerk JM, Fijnheer R, Heggelman BG, Dubois SV, Nievelstein RA, Kwee TC (2015) Prognostic superiority of the National Comprehensive Cancer Network International Prognostic Index over pretreatment whole-body volumetric-metabolic FDG-PET/CT metrics in diffuse large B-cell lymphoma. Eur J Haematol 94(6):532–539. doi:10.1111/ejh.12467

    Article  CAS  PubMed  Google Scholar 

  5. Melchardt T, Troppan K, Weiss L, Hufnagl C, Neureiter D, Trankenschuh W, Schlick K, Huemer F, Deutsch A, Neumeister P, Greil R, Pichler M, Egle A (2015) Independent prognostic value of serum markers in diffuse large B-cell lymphoma in the era of the NCCN-IPI. J Natl Compr Cancer Netw 13(12):1501–1508

    Google Scholar 

  6. Dunleavy K, Pittaluga S, Maeda LS, Advani R, Chen CC, Hessler J, Steinberg SM, Grant C, Wright G, Varma G, Staudt LM, Jaffe ES, Wilson WH (2013) Dose-adjusted EPOCH-rituximab therapy in primary mediastinal B-cell lymphoma. N Engl J Med 368(15):1408–1416. doi:10.1056/NEJMoa1214561

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Avivi I, Zilberlicht A, Dann EJ, Leiba R, Faibish T, Rowe JM, Bar-Shalom R (2013) Strikingly high false positivity of surveillance FDG-PET/CT scanning among patients with diffuse large cell lymphoma in the rituximab era. Am J Hematol 88(5):400–405. doi:10.1002/ajh.23423

    Article  CAS  PubMed  Google Scholar 

  8. Nakayama H, Aisa Y, Ito C, Shimazaki K, Katsumata Y, Hayashi H, Nakazato T (2015) Importance of histologic verification of positive positron emission tomography/computed tomography findings in the follow-up of patients with malignant lymphoma. Clin Lymphoma Myeloma Leuk 15(12):753–760. doi:10.1016/j.clml.2015.07.636

    Article  PubMed  Google Scholar 

  9. Bhojwani D, McCarville MB, Choi JK, Sawyer J, Metzger ML, Inaba H, Davidoff AM, Gold R, Shulkin BL, Sandlund JT (2015) The role of FDG-PET/CT in the evaluation of residual disease in paediatric non-Hodgkin lymphoma. Br J Haematol 168(6):845–853. doi:10.1111/bjh.13219

    Article  CAS  PubMed  Google Scholar 

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Acknowledgments

Author contributions

Hugo J.A. Adams was involved in the study design, article writing, and final approval of the manuscript. Thomas C. Kwee was involved in the study design, article writing, and final approval of the manuscript.

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Authors and Affiliations

  1. Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Heidelberglaan 100, 3584, CX, Utrecht, The Netherlands

    Hugo J. A. Adams & Thomas C. Kwee

Authors
  1. Hugo J. A. Adams
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  2. Thomas C. Kwee
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Corresponding author

Correspondence to Hugo J. A. Adams.

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Funding

This work was financially supported by an Alpe d’HuZes/Dutch Cancer Society Bas Mulder Award for T.C.K. (grant number 5409). Data collection, data analysis, and interpretation of data, writing of the paper, and decision to submit were left to the authors’ discretion and were not influenced by Alpe d’HuZes/Dutch Cancer Society.

Conflict of interest

The authors declare that they have no conflict of interests.

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Adams, H.J.A., Kwee, T.C. Seriously overestimated prognostic value of baseline and interim FDG-PET in diffuse large B cell lymphoma. Ann Hematol 95, 1367–1368 (2016). https://doi.org/10.1007/s00277-016-2710-2

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  • DOI: https://doi.org/10.1007/s00277-016-2710-2

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