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Clinical profile of megaloblastic anemia in China: a single center experience from MegA-1710 program over two decades

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References

  1. Maktouf C, Bchir A, Louzir H, Mdhaffer M et al (2006) Megaloblastic anemia in North Africa. Haematologica 91(7):990–991

    PubMed  Google Scholar 

  2. Savage D, Gangazaide I, Lindenbaum J et al (1994) Vitamin B 12 deficiency is the primary cause of megaloblastic anaemia in Zimbabwe. Br J Haematol 86(4):844–850

    Article  CAS  PubMed  Google Scholar 

  3. Harakati MS (1996) Pernicious anemia in Arabs. Blood Cells Mol Dis 22(2):98–103

    Article  CAS  PubMed  Google Scholar 

  4. Khanduri U, Sharma A (2007) Megaloblastic anaemia: prevalence and causative factors. Natl Med J India 20(4):172–175

    PubMed  Google Scholar 

  5. Toh BH, van Driel IR, Gleeson PA (1997) Pernicious anemia. N Engl J Med 337(20):1441–1448

    Article  CAS  PubMed  Google Scholar 

  6. Iqbal SP, Kakepoto GN, Iqbal SP (2009) Vitamin B12 deficiency a major cause of megaloblastic anaemia in patients attending a tertiary care hospital. 21(3):92–94

  7. Chan JC, Liu HS, Kho BC et al (1998) Megaloblastic anaemia in Chinese patients: a review of 52 cases. Hong Kong Med J 4(3):269–274

    PubMed  Google Scholar 

  8. Ng SC, Kuperan P, Chan KS et al (1988) Megaloblastic anaemia—a review from University Hospital Kuala Lumpur. Ann Acad Med Singap 17(2):261–266

    CAS  PubMed  Google Scholar 

  9. Akilzhanova A, Takamura N, Aoyagi K et al (2006) Fblic acid deficiency: main etiological factor of megaloblastic anemia in Kazakhstan. Am J Hematol 81(6):471

    Article  PubMed  Google Scholar 

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Acknowledgments

The authors thank all of the doctors and nurses in Therapeutic Centre of Anemic Diseases and the researcher team of Clinical Laboratory Centre for their professional assistance.

Author contributions

ZH completed the collection of the clinical data and analyzed and wrote the paper. YS, NN, JZ, XL, MG, and JH contributed to the clinical data collection. JS and YZ designed the research, wrote the paper, and approved the final manuscript.

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Authors and Affiliations

  1. State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 288 Nanjing Road, Tianjin, 300020, People’s Republic of China

    Zhendong Huang, Jun Shi, Yingqi Shao, Neng Nie, Jing Zhang, Xingxin Li, Meili Ge, Jinbo Huang & Yizhou Zheng

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  1. Zhendong Huang
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  2. Jun Shi
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  3. Yingqi Shao
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  4. Neng Nie
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  5. Jing Zhang
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  6. Xingxin Li
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  7. Meili Ge
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  8. Jinbo Huang
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  9. Yizhou Zheng
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Corresponding authors

Correspondence to Jun Shi or Yizhou Zheng.

Ethics declarations

The MegA-1710 program was approved by the Ethics Committees of the Institute of Hematology, Chinese Academy of Medical Sciences and Peking Union Medical College, according to guidelines of the Declaration of Helsinki (Ethics number: NI2015006-EC-1).

Conflict of interest

The authors declare that they have no conflict of interest.

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Huang, Z., Shi, J., Shao, Y. et al. Clinical profile of megaloblastic anemia in China: a single center experience from MegA-1710 program over two decades. Ann Hematol 95, 827–828 (2016). https://doi.org/10.1007/s00277-016-2609-y

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  • DOI: https://doi.org/10.1007/s00277-016-2609-y

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