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Changes in Condom Use During the First Year of HIV Treatment in Uganda and the Relationship to Depression

  • Original Article
  • Published:
Annals of Behavioral Medicine

Abstract

Purpose

We examined the effect of antiretroviral therapy (ART), and the predictive role of depression, on condom use with primary partners.

Methods

Data from three studies in Uganda were combined into a sample of 750 patients with a primary sex partner, with 502 starting ART and 248 entering HIV care, and followed for 12 months. Random-effects logistic regression models were used to examine the impact of ART, and the influence of baseline level and change in depression, on condom use with primary partners.

Results

At month 12, 61 % ART and 67 % non-ART patients were consistent condom users, compared to 44 and 41 % at baseline, respectively. Multivariate analysis revealed that consistent condom use increased similarly for ART and non-ART patients, and that minor depression at baseline and increased depression over time predicted inconsistent condom use.

Conclusions

Improved depression diagnosis and treatment could benefit HIV prevention.

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Acknowledgements

Funding for this research was contributed from grants from the National Institute of Mental Health (1R01MH083568), the National Institute for Child Health and Development (1R24HD056651) and Rockefeller Foundation (HE007).

Authors’ Statement of Conflict of Interest and Adherence to Ethical Standards

Authors Wagner, Ghosh-Dastidar, Slaughter, Akena, Nakasujja, and Musisi declare that they have no conflict of interest. All procedures, including the informed consent process, were conducted in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2000.

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Authors and Affiliations

  1. RAND Corporation, 1776 Main St., Santa Monica, CA, 90407, USA

    Glenn J. Wagner Ph.D., Bonnie Ghosh-Dastidar Ph.D. & Mary Ellen Slaughter M.S.

  2. Department of Psychiatry, Makerere University, College of Health Sciences, P.O. Box 7072, Mulago Hill, Kampala, Uganda

    Dickens Akena M.B.Ch.B., Noeline Nakasujja M.B.Ch.B. & Seggane Musisi M.B.Ch.B.

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  1. Glenn J. Wagner Ph.D.
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  2. Bonnie Ghosh-Dastidar Ph.D.
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Correspondence to Glenn J. Wagner Ph.D..

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Wagner, G.J., Ghosh-Dastidar, B., Slaughter, M.E. et al. Changes in Condom Use During the First Year of HIV Treatment in Uganda and the Relationship to Depression. ann. behav. med. 48, 175–183 (2014). https://doi.org/10.1007/s12160-013-9586-3

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  • DOI: https://doi.org/10.1007/s12160-013-9586-3

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