In SHR rats of different ages (22, 26, 30, 34, and 38 weeks), continuous 24-h telemetric monitoring of BP and HR was performed. The amplitude and power of oscillations of diastolic BP significantly decreased at the later stages of arterial hypertension (38 weeks), which was considered as a poor prognostic marker. We also observed a significant decrease in the mean daytime, nighttime, and maximum HR and mesor on weeks 30 and 34, but not on week 38, which can reflect triggering of the adaptive response followed by its exhaustion.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
V. N. Burdin, I. V. Motov, V. V. Grebennikova, and I. A. Novitskii, Sovrem. Probl. Nauki Obrazov., No. 6, 125-128 (2008).
D. G. Gubin, G. D. Gubin, and L. I. Gapon, Vestn. Aritmol., No. 16, 84-94 (2000).
L. M. Makarov, Kardiologiya, No. 11, 34-37 (1999).
D. A. Huetteman and H. Bogie, Methods Mol. Biol., 573, 57-73 (2009).
K. Kramer and R. Remie, Methods Mol. Med., 108, 51-62 (2005).
J. A. Potkay, Biomed. Microdevices, 10, No. 3, 379-392 (2008).
K. M. Vaze and V. K. Sharma, Chronobiol. Int., 30, No. 4, 413-433 (2013).
P. Zuther, S. Gorbey, and B. Lemmer, Chronos-Fit 1.06 (2009) [URL: http://www.ma.uni-heidelberg.de/inst/phar/lehre/chrono.html.]
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 158, No. 12, pp. 681-683, December, 2014
Rights and permissions
About this article
Cite this article
Blagonravov, M.L., Frolov, V.A., Goryachev, V.A. et al. Features of the Structure of the Circadian Rhythm of Blood Pressure and Heart Rate under Genetically Determined Hypertension in the Experiment. Bull Exp Biol Med 158, 723–725 (2015). https://doi.org/10.1007/s10517-015-2846-4
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-015-2846-4