Abstract
Since the early 2000s, many types of positron emission tomography (PET) scanners dedicated to breast imaging for the diagnosis of breast cancer have been introduced. However, conventional performance evaluation methods developed for whole-body PET scanners cannot be used for such devices. In this study, we developed phantom tools for evaluating the quantitative accuracy of positron emission mammography (PEM) and dedicated-breast PET (dbPET) scanners using novel traceable point-like 68Ge/68 Ga sources. The PEM phantom consisted of an acrylic cube (100 × 100 × 40 mm) and three point-like sources. The dbPET phantom comprised an acrylic cylinder (ø100 × 100 mm) and five point-like sources. These phantoms were used for evaluating the fundamental responses of clinical PEM and dbPET scanners to point-like inputs in a medium. The results showed that reasonable recovery values were obtained based on region-of-interest analyses of the reconstructed images. The developed phantoms using traceable 68Ge/68 Ga point-like sources were useful for evaluating the physical characteristics of PEM and dbPET scanners. Thus, they offer a practical, reliable, and universal measurement scheme for evaluating various types of PET scanners using common sets of sealed sources.
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Acknowledgements
We would like to thank Takahiro Yamada (Kinki University), Yasushi Sato (AIST), Mikio Matsuo, Hidetaka Ishizu, and Takahiro Mikamoto (JRIA) for their collaboration in the development and production of the traceable 68Ge/68Ga point-like sources. We would also like to thank Kentaro Takahashi (Kitasato University Graduate School) for help with related data analyses. Finally, we would like to thank Kenta Miwa (Fukushima Medical University), and Noriaki Miyaji (Cancer Institute Hospital of JFCR) for their collaboration with the multicenter studies using traceable point-like sources. This study was supported in part by JSPS KAKENHI JP18K07688 and JP21K07605.
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Okamoto, M., Hasegawa, T., Oda, K. et al. Dedicated phantom tools using traceable 68Ge/68Ga point-like sources for dedicated-breast PET and positron emission mammography scanners. Radiol Phys Technol 16, 49–56 (2023). https://doi.org/10.1007/s12194-022-00692-0
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DOI: https://doi.org/10.1007/s12194-022-00692-0