Abstract
Purpose of Review
The purpose of this review paper is to describe the 24-h urine collection in terms of its utility, collection process, and common problems with its acquisition.
Recent Findings
Although 24-h urine collections are standard of care for high-risk stone formers, several nuances in test acquisition including inaccurate urine collections 50% of the time and poor patient compliance limit its potential utility. Compliance in obtaining 24-h urine collections has been shown to be improved in patients who have not undergone surgical treatment of urinary calculi, patients with metabolic stone disease or family history of stone disease, Caucasian ethnicity, and in those with more sedentary occupations. Studies show conflicting data of compliance regarding patient age and gender.
Summary
Physicians must understand the difficulties regarding 24-h urine collections including patient compliance, variability between collections, and complexities with interpretation to best utilize this tool in guiding clinical management for the treatment of nephrolithiasis.
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References
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Alice Xiang, Alex Nourian, and Eric Ghiraldi each declare no potential conflicts of interest. Dr. Friedlander is a consultant for Travere Therapeutics, and has received personal fees outside the submitted work.
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Xiang, A., Nourian, A., Ghiraldi, E. et al. Improving Compliance with 24-H Urine Collections: Understanding Inadequacies in the Collection Process and Risk Factors for Poor Compliance. Curr Urol Rep 22, 38 (2021). https://doi.org/10.1007/s11934-021-01057-7
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DOI: https://doi.org/10.1007/s11934-021-01057-7