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Predictors of Return to Work for People with Anxiety or Depression Participating in a Randomized Trial Investigating the Effect of a Supported Employment Intervention

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Abstract

Purpose Common mental disorders have a severe impact on society and individuals; rates of unemployment and disability pensions are high. Knowing which factors facilitate or hinder people’s return to work is important when designing effective vocational rehabilitation interventions. Methods We conducted secondary analyses on data from 289 participants with depression or anxiety included in the Individual Placement and Support modified for people with mood and anxiety disorders (IPS-MA) trial. Associations of baseline characteristics and employment or education after 24 months were tested in univariate logistic regression analyses, variables with a p-value below 0.1 were included in multivariate analyses. Results In the univariate analyses, self-reported level of functioning (p = 0.032), higher age (p = 0.070), and higher level of readiness to change (p = 0.001) were associated with the outcome and included in the multivariate analysis. Only age (p = 0.030) and readiness to change (p = 0.003) remained significantly associated with return to work or education after 24 months in the multivariate analysis. Conclusion Higher age and lower readiness to change were associated with a lower chance of having returned to work or education. Factors modifying the effect of higher age should be identified, just as vocational rehabilitation should focus on improving factors related to people’s readiness to change.

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Data Availability

Data are available from the corresponding author upon request.

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References

  1. Wilson RL. Mental health and substance use. In: Mental health. Cambridge University Press; 2018. p. 175–201.

  2. OECD. Mental health and work: Denmark. Paris: OECD Publishing; 2013. (Mental Health and Work). http://www.oecd-ilibrary.org/employment/mental-health-and-work-denmark_9789264188631-en. Accessed 28 May 2018.

  3. Flachs E, Eriksen L, Koch M, Ryd J, Dibba E, Skov-Ettrup L, et al. Sygdomsbyrden i Danmark [Internet]. Statens Institut for Folkesundhed, Syddansk Universitet. København; 2015. https://www.sst.dk/da/sygdom-og-behandling/~/media/00C6825B11BD46F9B064536C6E7DFBA0.ashx. Accessed 21 Feb 2022.

  4. Drake RE, Bond GR, Becker DR. Individual placement and support: an evidence-based approach to supported employment. Vol. 9780199734, Individual placement and support: an evidence-based approach to supported employment. Oxford University Press; 2013. http://ezproxy.library.ubc.ca/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=psyh&AN=2012-29673-000&site=ehost-live&scope=site. Accessed 26 Feb 2018.

  5. Christensen TN, Wallstrøm IG, Stenager E, Bojesen AB, Gluud C, Nordentoft M, et al. Effects of individual placement and support supplemented with cognitive remediation and work-focused social skills training for people with severe mental illness: a randomized clinical trial. JAMA Psychiat. 2019;76(12):1232–1240.

    Article  Google Scholar 

  6. Modini M, Tan L, Brinchmann B, Wang M-J, Killackey E, Glozier N, et al. Supported employment for people with severe mental illness: systematic review and meta-analysis of the international evidence. Br J Psychiatry. 2016;209(1):14–22.

    Article  PubMed  Google Scholar 

  7. Hellström L, Pedersen P, Christensen TN, Wallstroem IG, Bojesen AB, Stenager E, et al. Vocational outcomes of the individual placement and support model in subgroups of diagnoses, substance abuse, and forensic conditions: a systematic review and analysis of pooled original data. J Occup Rehabil. 2021;31(4):699–710.

    Article  PubMed  Google Scholar 

  8. Bejerholm U, Larsson ME, Johanson S. Supported employment adapted for people with affective disorders—a randomized controlled trial. J Affect Disord. 2017;207:212–220.

    Article  PubMed  Google Scholar 

  9. Johanson S, Markström U, Larsson ME, Bejerholm U. Implementation of a novel return-to-work approach for persons with affective disorders in a traditional vocational rehabilitation context: a case study. Int J Ment Health Syst. 2020;14(1):1–12.

    Article  Google Scholar 

  10. Hellström L, Bech P, Hjorthøj C, Nordentoft M, Lindschou J, Eplov LF. Effect on return to work or education of individual placement and support modified for people with mood and anxiety disorders: results of a randomised clinical trial. Occup Environ Med. 2017;74(10):717–725.

    Article  PubMed  Google Scholar 

  11. Bond GR, Drake RE, Becker DR. An update on randomized controlled trials of evidence-based supported employment. Psychiatr Rehabil J. 2008;31(4):280–290.

    Article  PubMed  Google Scholar 

  12. Lammerts L, Schaafsma FG, Eikelenboom M, Vermeulen SJ, van Mechelen W, Anema JR, et al. Longitudinal associations between biopsychosocial factors and sustainable return to work of sick-listed workers with a depressive or anxiety disorder. J Occup Rehabil. 2016;26(1):70–79.

    Article  PubMed  Google Scholar 

  13. Vemer P, Bouwmans CA, Zijlstra-Vlasveld MC, van Der Feltz-Cornelis CM, Hakkaart-van Roijen L, Roijen LH. Let’s get back to work: survival analysis on the return-to-work after depression. Neuropsychiatr Dis Treat. 2013;9:1637–1644.

    PubMed  PubMed Central  Google Scholar 

  14. Dewa CS, Hoch JS, Lin E, Paterson M, Goering P. Pattern of antidepressant use and duration of depression-related absence from work. Br J Psychiatry. 2003;183:507–513.

    Article  PubMed  Google Scholar 

  15. Hees HL, Koeter MWJ, Schene AH. Predictors of long-term return to work and symptom remission in sick-listed patients with major depression. J Clin Psychiatry. 2012;73:1048–1055.

    Article  Google Scholar 

  16. Lamberg T, Virtanen P, Vahtera J, Koskenvuo M. Unemployment, depressiveness and disability retirement: a follow-up study of the Finnish HeSSup population sample. Soc Psychiatry Psychiatr Epidemiol. 2010;45(2):259–264.

    Article  PubMed  Google Scholar 

  17. Koopmans PC, Roelen CAM, Groothoff JW. Sickness absence due to depressive symptoms. Int Arch Occup Environ Health. 2008;81(6):711–719.

    Article  CAS  PubMed  Google Scholar 

  18. Tolman RM, Himle JH, Bybee D, Abelson JL, Van Etten-Lee M. Impact of social anxiety disorder on employment among women receiving welfare benefits. Psychiatr Serv. 2009;60(1):61–66.

    Article  PubMed  Google Scholar 

  19. Nielsen MBD, Bültmann U, Madsen I, Martin M, Christensen U, Diderichsen F, et al. Health, work, and personal-related predictors of time to return to work among employees with mental health problems. Disabil Rehabil. 2012;34(15):1311–1316.

    Article  PubMed  Google Scholar 

  20. Lagerveld SE, Bültmann U, Franche RL, Van Dijk FJH, Vlasveld MC, Van Der Feltz-Cornelis CM, et al. Factors associated with work participation and work functioning in depressed workers: a systematic review. J Occup Rehabil. 2010;20(3):275–292.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  21. Bultmann U, Rugulies R, Lund T, Christensen KB, Labriola M, Burr H. Depressive symptoms and the risk of long-term sickness absence: a prospective study among 4747 employees in Denmark. Soc Psychiatry Psychiatr Epidemiol. 2006;41(11):875–880.

    Article  PubMed  Google Scholar 

  22. Van Duin D, Kroon H, Veling W, Van Weeghel J. Does cognitive remediation enhance the vocational recovery of young people with first episode psychosis using individual placement and support? Results of the CREW study: a multisite randomized controlled trial in the Netherlands. Early intervention in psychiatry conference IEPA 11th international conference early interventions in mental health—“prevention early Interv broadening scope” United states. 2018;12(Supplement 1):17. https://doi.org/10.1002/central/CN-01653446/full

  23. McGurk SR, Mueser KT. Cognitive functioning, symptoms, and work in supported employment: a review and heuristic model. Schizophr Res. 2004;70(2–3):147–173.

    Article  PubMed  Google Scholar 

  24. Ervasti J, Joensuu M, Pentti J, Oksanen T, Ahola K, Vahtera J, et al. Prognostic factors for return to work after depression-related work disability: a systematic review and meta-analysis. J Psychiatr Res. 2017;95:28–36.

    Article  PubMed  Google Scholar 

  25. Nieuwenhuijsen K, Noordik E, Van Dijk FJH, Van Der Klink JJ. Return to work perceptions and actual return to work in workers with common mental disorders. J Occup Rehabil. 2013;23(2):290–299.

    Article  PubMed  Google Scholar 

  26. Nigatu Y, Liu Y, Uppal M, McKinney S, Gillis K, Rao S, et al. Prognostic factors for return to work of employees with common mental disorders: a meta-analysis of cohort studies. Soc Psychiatry Psychiatr Epidemiol. 2017;52(10):1205–1215.

    Article  PubMed  Google Scholar 

  27. Sandin K, Anyan F, Osnes K, Gunnarsdatter H, Gjengedal R, Risberg Leversen JS, et al. Sick leave and return to work for patients with anxiety and depression: a longitudinal study of trajectories before, during and after work-focused treatment. BMJ Open. 2021;11(9):e046336.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Hellstrom L, Bech P, Nordentoft M, Lindschou J, Eplov LF. The effect of IPS-modified, an early intervention for people with mood and anxiety disorders: study protocol for a randomised clinical superiority trial. Trials. 2013;14(1):442.

    Article  PubMed  PubMed Central  Google Scholar 

  29. Substance Abuse and Mental Health Services Administration. Supported Employment: Evaluating your program [Internet]. SMA-08-436. Rockville, MD: Center for Mental Health Services, Substance Abuse and Mental Health Services Administration, U.S. Department of Health and Human Services; 2009. www.samhsa.gov. Accessed 1 Mar 2022.

  30. The Danish Agency for Labour Market and Recruitment. The DREAM database, Statistics Denmark [DREAM databasen, Danmarks Statistik]. Copenhagen, Denmark: The National Labour Market Authority; 2015. http://www.dst.dk/da/TilSalg/Forskningsservice/Data/Andre_Styrelser.aspx

  31. The Civil Registration System (CPR-register). https://www.cpr.dk/. Accessed 17 Sep 2017.

  32. The Danish Customs and Tax Administration (SKAT). http://www.skat.dk/. Accessed 25 Jan 2017.

  33. Bech P. Clinical psychometrics. Oxford: Wiley-Blackwell; 2012.

    Book  Google Scholar 

  34. O’Sullivan RL, Fava M, Agustin C, Baer L, Rosenbaum JF. Sensitivity of the six-item Hamilton Depression Rating Scale. Acta Psychiatr Scand. 1997;95(5):379–384.

    Article  PubMed  Google Scholar 

  35. Maier W, Buller R, Philipp M, Heuser I. The Hamilton Anxiety Scale: reliability, validity and sensitivity to change in anxiety and depressive disorders. J Affect Disord. 1988;14:61–68.

    Article  CAS  PubMed  Google Scholar 

  36. Nafees B, de Jonge PV, Stull D, Pascoe K, Price M, Clarke A, et al. Reliability and validity of the Personal and Social Performance scale in patients with schizophrenia. Schizophr Res. 2012;140(1–3):71–76.

    Article  PubMed  Google Scholar 

  37. Hellstrom LC, Eplov LF, Nordentoft M, Ostergaard SD, Bech P. The Diagnostic Apathia Scale predicts the ability to return to work following depression or anxiety. ACTA Neuropsychiatr. 2014;26(6):364–371.

    Article  CAS  PubMed  Google Scholar 

  38. Sheehan DV, Harnett-Sheehan K, Raj BA. The measurement of disability. Int Clin Psychopharmacol. 1996;11(Suppl 3):89–95.

    Article  PubMed  Google Scholar 

  39. Miller WR, Johnson WR. A natural language screening measure for motivation to change. Addict Behav. 2008;33(9):1177–1182.

    Article  PubMed  Google Scholar 

  40. IBM Corp. Released 2017. IBM SPSS Statistics for Windows, Version 25.0. Armonk, NY: IBM Corp.

  41. Riihimaki K, Vuorilehto M, Isometsa E. A 5-year prospective study of predictors for functional and work disability among primary care patients with depressive disorders. Eur Psychiatry. 2015;30(1):51–57.

    Article  CAS  PubMed  Google Scholar 

  42. Hees HL, Koeter MWJ, Schene AH. Longitudinal relationship between depressive symptoms and work outcomes in clinically treated patients with long-term sickness absence related to major depressive disorder. J Affect Disord. 2013;148(2–3):272–277. https://doi.org/10.1016/j.jad.2012.12.007.

    Article  PubMed  Google Scholar 

  43. Mattila-Holappa P, Ervasti J, Joensuu M, Ahola K, Pentti J, Oksanen T, et al. Do predictors of return to work and recurrence of work disability due to mental disorders vary by age? A cohort study. Scand J Public Health. 2017;45(2):178–184.

    Article  PubMed  Google Scholar 

  44. Christensen T, Wallstrøm I, Bojesen A, Nordentoft M, Eplov L. Predictors of work and education among people with severe mental illness who participated in the Danish individual placement and support study: findings from a randomized clinical trial. Soc Psychiatry Psychiatr Epidemiol. 2021;56(9):1669–1677.

    Article  PubMed  Google Scholar 

  45. Nielsen MBD, Bültmann U, Amby M, Christensen U, Diderichsen F, Rugulies R, et al. Return to work among employees with common mental disorders: study design and baseline findings from a mixed-method follow-up study. Scand J Public Health. 2010;38(8):864–872.

    Article  PubMed  Google Scholar 

  46. Brenninkmeijer V, Lagerveld S, Blonk R, Schaufeli W, Wijngaards-de Meij L. Predicting the effectiveness of work-focused CBT for common mental disorders: the influence of baseline self-efficacy, depression and anxiety. J Occup Rehabil. 2019;29(1):31–41.

    Article  PubMed  Google Scholar 

  47. Reme SE, Grasdal AL, Lovvik C, Lie SA, Overland S, Løvvik C, et al. Work-focused cognitive-behavioural therapy and individual job support to increase work participation in common mental disorders: a randomised controlled multicentre trial. Occup Environ Med. 2015;72(10):745–752.

    Article  PubMed  Google Scholar 

  48. Kukla M, Salyers MP, Strasburger AM, Johnson-Kwochka A, Amador E, Lysaker PH. Work-focused cognitive behavioral therapy to complement vocational services for people with mental illness: pilot study outcomes across a 6-month posttreatment follow-up. Psychiatr Rehabil J. 2019;42(4):366–371.

    Article  PubMed  Google Scholar 

  49. Ekberg K, Wåhlin C, Persson J, Bernfort L, Öberg B, Wahlin C, et al. Early and late return to work after sick leave: predictors in a cohort of sick-listed individuals with common mental disorders. J Occup Rehabil. 2015;25(3):627–637. https://doi.org/10.1007/s10926-015-9570-9.

    Article  PubMed  Google Scholar 

  50. de Vries H, Fishta A, Weikert B, Rodriguez Sanchez A, Wegewitz U. Determinants of sickness absence and return to work among employees with common mental disorders: a scoping review. J Occup Rehabil. 2018;28:293–417.

    Article  Google Scholar 

  51. Banerjee S, Chatterji P, Lahiri K. Identifying the mechanisms for workplace burden of psychiatric illness. Med Care. 2014;52(2):112–120.

    Article  PubMed  Google Scholar 

  52. Mojtabai R, Stuart EA, Hwang I, Eaton WW, Sampson N, Kessler RC. Long-term effects of mental disorders on educational attainment in the National Comorbidity Survey ten-year follow-up. Soc Psychiatry Psychiatr Epidemiol. 2015;50(11):1657–1168.

    Article  PubMed  PubMed Central  Google Scholar 

  53. Fyhn T, Øverland S, Reme SE. Predictors of employment in people with moderate to severe mental illness participating in a randomized controlled trial of Individual Placement and Support (IPS). Int J Soc Psychiatry. 2021;67(2):150–157. https://doi.org/10.1177/0020764020934841.

    Article  PubMed  Google Scholar 

  54. Merikangas KR, Zhang H, Avenevoli S, Acharyya S, Neuenschwander M, Angst J. Longitudinal trajectories of depression and anxiety in a prospective community study: the Zurich cohort study. Arch Gen Psychiatry. 2003;60:993–1000.

    Article  PubMed  Google Scholar 

  55. Batelaan NM, Rhebergen D, Spinhoven P, Van Balkom AJ, Penninx BWJH. Two-year course trajectories of anxiety disorders: do DSM classifications matter? J Clin Psychiatry. 2014;75(9):985–993.

    Article  PubMed  Google Scholar 

  56. Arends I, Almansa J, Stansfeld SA, Amick BC, van der Klink JJL, Bültmann U. One-year trajectories of mental health and work outcomes post return to work in patients with common mental disorders. J Affect Disord. 2019;257:263–270.

    Article  CAS  PubMed  Google Scholar 

  57. Hellström L, Madsen T, Nordentoft M, Eplov LF. Trajectories of symptoms of anxiety and depression among people on sick leave with mood or anxiety disorders: secondary analysis from a randomized controlled trial. J Psychiatr Res. 2021;1(137):250–257.

    Article  Google Scholar 

  58. Christensen TN, Nielsen IG, Stenager E, Morthorst BR, Lindschou J, Nordentoft M, et al. Individual placement and support supplemented with cognitive remediation and work-related social skills training in Denmark: study protocol for a randomized controlled trial. Trials. 2015;16(1):280.

    Article  PubMed  PubMed Central  Google Scholar 

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All authors participated in the planning and design of the study, interpretation of the results, and have read and critically revised the manuscript. LH conducted the data analysis with valuable support from ABB. LH wrote the first draft of the manuscript.

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Correspondence to Lone Hellström.

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All authors declare no conflicts of interest.

Ethical Approval

The IPS-MA trial was approved by The Regional Ethics Committees of the Capital Region (journal no: H-2-2011-FSP20), reported to the Danish Data Protection Agency (Journal no: 2007-58-0015, local journal no: RHP-2011-20), and registered at www.clinicaltrials.gov (identifier: NCT01721824).

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In the original trial all participants provided written and oral consent.

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Consent to participate was obtained from all participants, and the study was reported to the Danish Data Protection Agency (Journal no: 2007-58-0015, local journal no: RHP-2011-20).

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Hellström, L., Christensen, T.N., Bojesen, A.B. et al. Predictors of Return to Work for People with Anxiety or Depression Participating in a Randomized Trial Investigating the Effect of a Supported Employment Intervention. J Occup Rehabil 33, 61–70 (2023). https://doi.org/10.1007/s10926-022-10046-7

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