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Nocturia and Blood Pressure Elevation in Adolescents

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Abstract

Nocturia has been increasingly recognized as a manifestation of various non-urological conditions including hypertension. In adults, blood pressure (BP) elevation has been identified as a robust correlate of nocturia, but such a relationship has not been studied in pediatric populations where nocturia is often attributed to hormonal, sleep, physiological or psychological disorders. Accordingly, this study aimed to determine the relationship between nocturia and BP elevation in adolescents. We prospectively studied 100 patients, aged 10–18 years, recruited from pediatric clinics at our institution. Nocturia (defined as ≥ 1 voids on voiding diary analysis) was present in 45% of the study sample (range: 1–4 voids/night). 37% of subjects self-reported awakening to urinate, and 34% of subjects had BP elevation according to age-dependent thresholds from current Pediatrics guidelines. On multivariate analyses, BP elevation was strongly associated with nocturia determined by both voiding diary (OR 26.2, 95% CI: 6.5, 106.0) and self-report. Conversely, nocturia was associated with increased odds of elevated BP by diary (26.3, 95% CI: 6.5, 106.4) and self-report (OR 8.1, 95% CI: 3.2, 20.5). In conclusion, nocturia appears to be common and is strongly associated with BP elevation in adolescents. These findings suggest that eliciting a history of nocturia holds promise as a simple method of identifying adolescents at risk for hypertension.

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Authors and Affiliations

  1. Division of Cardiovascular Medicine, State University of New York Downstate Health Sciences University, 450 Clarkson Avenue, MSC 1199, Brooklyn, NY, 11203- 2098, USA

    Tasmia Promi, Gulzhan Tologonova, Louis Salciccioli & Jason M. Lazar

  2. College of Nursing, State University of New York Downstate Health Sciences University, Brooklyn, NY, USA

    Marie-Claire Roberts

  3. Department of Pediatrics, State University of New York Downstate Health Sciences University, Brooklyn, NY, USA

    Meseret Tena, Sarita Dhuper, Oluwatoyin Bamgbola, Monique Hanono, Stephen Wadowski & Elka Jacobson-Dickman

  4. Department of Urology, State University of New York Downstate Health Sciences University, Brooklyn, NY, USA

    Jeffrey P. Weiss

  5. Department of Human Structure and Repair, Ghent University Hospital, Ghent, Belgium

    Karel Everaert

  6. Department of Internal Medicine and Pediatrics, Ghent University Hospital, Ghent, Belgium

    Tine DeBacker

  7. Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA

    Thomas Monaghan

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  1. Tasmia Promi
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Promi, T., Tologonova, G., Roberts, MC. et al. Nocturia and Blood Pressure Elevation in Adolescents. J Community Health 49, 379–384 (2024). https://doi.org/10.1007/s10900-023-01307-4

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