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Circulation of unusual and diverse enteric virus strains in adults with acute gastroenteritis: a study from Pune (Maharashtra), Western India

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Abstract

In India, studies on the epidemiological and genetic characteristics of enteric viruses in adults with acute gastroenteritis (AGE) are lacking. In this study, fecal samples (n = 110) from adults with acute gastroenteritis in Pune, Western India, were tested for six enteric viruses, and the prevalence of these viruses was as follows: rotavirus A (RVA), 38.5%; enterovirus (EV), 23.1%; astrovirus (AstV), 23.1%; adenovirus (AdV), 7.7%; human bocavirus (HBoV), 7.7%; norovirus (NoV), 0%. Circulation of the RVA G1P[8], G3P[8], G9P[4], CVA-10, echovirus E13, EVC-116, AstV-5, AstV-2, HBoV-1, and AdVC-2 types was observed. When compared to the RotaTeq, Rotarix, and RotaVac vaccine strains, antigenic changes were found in the A, B, C, and F regions of the RVA strains. The circulation of genetically diverse, unusual enteric virus strains, reported here for the first time in adults with acute gastroenteritis, warrants multi-center hospital-based surveillance studies across the country.

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All data generated or analyzed during this study are included in this Published article and its supplementary PDF file.

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Acknowledgements

The authors are thankful to the Director, ICMR-National Institute of Virology, Pune, India, for providing support. The help of Mr. P.S. Jadhav during sample collection from the hospitals is gratefully acknowledged. Thanks are due to Dr. A.N. Borhalkar from Shreyas Clinic, Pune, for providing the clinical samples and patients’ histories.

Funding

This work was supported by funds granted by ICMR-National Institute of Virology.

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Authors and Affiliations

  1. Enteric Viruses Group, Indian Council of Medical Research (ICMR)-National Institute of Virology, 20-A, Dr. Ambedkar Road, Pune, Maharashtra, 411001, India

    Vaishali S. Tatte & Varanasi Gopalkrishna

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  1. Vaishali S. Tatte
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  2. Varanasi Gopalkrishna
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Correspondence to Varanasi Gopalkrishna.

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Tatte, V.S., Gopalkrishna, V. Circulation of unusual and diverse enteric virus strains in adults with acute gastroenteritis: a study from Pune (Maharashtra), Western India. Arch Virol 168, 160 (2023). https://doi.org/10.1007/s00705-023-05771-0

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