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Comparison of the one-year outcomes of bariatric surgery in adolescents and young adults: a matched case–control study, Tehran Obesity Treatment Study (TOTS)

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Abstract

Purposes

The increasing use of bariatric surgery in adolescents has raised some concerns regarding the postoperative outcomes and the optimal time of surgery at young ages. However, no study has yet compared the weight loss and comorbidity resolution following bariatric surgery between adolescents and young adults.

Methods

This study was conducted on a case group of adolescents (aged 11–18) and a control group of young adults (aged 19–29) undergoing bariatric surgery (sleeve gastrectomy or gastric bypass). The two groups were matched in terms of gender, body mass index (BMI), and surgery type and were assessed regarding the surgical outcomes at 1 year after surgery.

Results

The baseline characteristics of the adolescents (n = 118, mean age: 17.0 ± 1.6 years) and young adults (n = 236, mean age: 25.2 ± 3.2 years) were similar, as well as surgery-associated complications. The mean loss of BMI (− 15.4 ± 3.6 vs. −15.8 ± 4.6 kg/m2) and 12-month percentage of excess weight loss (80.4 ± 20.1 vs. 80.2 ± 20.1%) were similar in the two groups. Both groups showed parallel reductions in the cardiovascular risk factors. The remission of hypertension, diabetes mellitus, and dyslipidemia was similar between the groups. The increase in the hemoglobin level and copper deficiency was greater in young adults, whereas the increase in ferritin deficiency was greater in adolescents.

Conclusion

Similar to young adults, bariatric surgery is an effective and safe method to achieve weight loss, resolve obesity-related comorbidities, and improve cardiovascular risk factors in the adolescents.

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Acknowledgments

The authors would like to thank the hospital staff, study assistants, and coordinators that took part in this research. In addition, we would like to give special thanks to Mohammadreza Golsibi for his assistance and support of the electronic data collection system

Funding

None.

Author information

Authors and Affiliations

  1. Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Shayan Aryannezhad, Farhad Hosseinpanah, Maryam Mahdavi, Majid Valizadeh & Maryam Barzin

  2. Department of Surgery, Faculty of Medicine, Tehran Obesity Treatment Center, Shahed University, Tehran, Iran

    Alireza Khalaj

  3. Department of Pediatrics, Faculty of Medicine, Shahed University, Tehran, Iran

    Seyed Mohammad Bagher Akhavirad

Authors
  1. Shayan Aryannezhad
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  2. Farhad Hosseinpanah
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  3. Alireza Khalaj
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  4. Maryam Mahdavi
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  5. Majid Valizadeh
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  6. Seyed Mohammad Bagher Akhavirad
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  7. Maryam Barzin
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Corresponding author

Correspondence to Maryam Barzin.

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Conflict of interest

Aryannezhad S, Hosseinpanah F, Khalaj A, Mahdavi M, Valizadeh M, Akhavirad MB and Barzin M have no conflict of interest.

Ethical approval

This study was approved by the institutional review board (no. IR.SBMU.ENDOCRINE.REC 1397.0592018-05-08). Informed consent was obtained from all the participants included in the study. All procedures performed were in accordance with the ethical standards of the institutional and/or national research committee and 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Aryannezhad, S., Hosseinpanah, F., Khalaj, A. et al. Comparison of the one-year outcomes of bariatric surgery in adolescents and young adults: a matched case–control study, Tehran Obesity Treatment Study (TOTS). Surg Today 51, 1764–1774 (2021). https://doi.org/10.1007/s00595-021-02281-x

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  • DOI: https://doi.org/10.1007/s00595-021-02281-x

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