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Funding
This work was supported by JSPS KAKENHI Grant Number 17K17584, 16H06279 (PAGS), 19K22589, SRF, JST ERATO JPMJER1902, AMED-CREST JP21gm1010009, the Food Science Institute Foundation, Astellas Foundation for Research on Metabolic Disorders, and Kato Memorial Bioscience Foundation. This work was partly performed in the Cooperative Research Project Program of the Medical Institute of Bioregulation, Kyushu University.
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YT and RY are equally contributing first authors. YT and RY designed the study. YT, RY and JK performed the study and analyzed the data. RY, HM, KK, SF, YG, KN, TH, YK, and YS provided the measurements for the microbiome and metabolome analysis. SFukudo provided scientific insight to complete the study. YT wrote the first draft of the manuscript. SFukudo prepared the final version of the manuscript. All authors contributed to data interpretation, writing, and final approval of the manuscript.
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Tanaka, Y., Yamashita, R., Kawashima, J. et al. Further notice of omics profiles of fecal and oral microbiota change in irritable bowel syndrome patients with diarrhea and symptom exacerbation. J Gastroenterol 58, 427–428 (2023). https://doi.org/10.1007/s00535-022-01951-y
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DOI: https://doi.org/10.1007/s00535-022-01951-y