Overview
Part of the book series: Advances in Anatomy, Embryology and Cell Biology (ADVSANAT, volume 203)
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Table of contents (7 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Adult neurogenesis has been questioned for many years. In the early 1900s, a dogma was established that denied new neuron formation in the adult brain. In the last century however, new discoveries have demonstrated the real existence of proliferation in the adult brain, and in the last decade, these studies led to the identification of neural stem cells in mammals. Adult neural stem cells are undifferentiated cells that are present in the adult brain and are capable of dividing and differentiating into glia and new neurons. Newly formed neurons terminally differentiate into mature neurons in the olfactory bulb and the dentate gyrus of the hippocampus. Since then, a number of new research lines have emerged whose common objective is the phenotypical and molecular characterization of brain stem cells. As a result, new therapies are successfully being applied to animal models for certain neurodegenerative diseases or stroke. At present, and in years to come, this finding extends to the adult human brain, and gives reason and hope to all the previous studies.
Bibliographic Information
Book Title: Identification and Characterization of Neural Progenitor Cells in the Adult Mammalian Brain
Authors: Jose Manuel Garcia-Verdugo, Arturo Alvarez-Buylla, Sara Gil-Perotín
Series Title: Advances in Anatomy, Embryology and Cell Biology
DOI: https://doi.org/10.1007/978-3-540-88719-5
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2009
Softcover ISBN: 978-3-540-88718-8Published: 30 April 2009
eBook ISBN: 978-3-540-88719-5Published: 21 April 2009
Series ISSN: 0301-5556
Series E-ISSN: 2192-7065
Edition Number: 1
Number of Pages: XII, 104
Number of Illustrations: 16 b/w illustrations, 15 illustrations in colour
Topics: Neurosciences, Stem Cells
Industry Sectors: Biotechnology, Consumer Packaged Goods, Health & Hospitals, Pharma